Correlation of central venous and arterial blood gas measurements in mechanically ventilated trauma patients

Darren Malinoski, Samuel R. Todd, D. Sue Slone, Richard Mullins, Martin Schreiber

    Research output: Contribution to journalArticle

    45 Citations (Scopus)

    Abstract

    Hypothesis: Central venous blood gas (VBG) measurements of pH, PCO 2, and base excess can be substituted for the same values obtained from an arterial blood gas (ABG) analysis in mechanically ventilated trauma patients, obviating the need for arterial puncture. Design and Setting: Prospective comparison of 99 sets of VBGs and ABGs at a level 1 academic trauma center. Patients: A consecutive sample of 25 trauma patients admitted to the intensive care unit who required mechanical ventilation and had both central venous and arterial catheters. Main Outcome Measures: Pearson correlations and Bland-Altman limits of agreement (LOAs) for pH, PCO2, and base excess values from each set of VBGs and ABGs. Results: When VBG and ABG values were compared, pH had R=0.92, P2, R=0.88, P2 of 50 mm Hg had 100% sensitivity and 84% specificity for determining significant hypercarbia (arterial PCO2>50 mm Hg). Conclusions: Central venous and arterial PCO2, pH, and base excess values correlate well, but their LOAs represent clinically significant ranges that could affect management. Although VBGs cannot be substituted for ABGs in mechanically ventilated trauma patients during the initial phases of resuscitation, clinically reliable conclusions can be reached with VBG analysis.

    Original languageEnglish (US)
    Pages (from-to)1122-1125
    Number of pages4
    JournalArchives of Surgery
    Volume140
    Issue number11
    DOIs
    StatePublished - Nov 2005

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    Gases
    Blood Gas Analysis
    Wounds and Injuries
    Central Venous Catheters
    Hypercapnia
    Trauma Centers
    Punctures
    Artificial Respiration
    Resuscitation
    Intensive Care Units
    Outcome Assessment (Health Care)
    Sensitivity and Specificity

    ASJC Scopus subject areas

    • Surgery

    Cite this

    Correlation of central venous and arterial blood gas measurements in mechanically ventilated trauma patients. / Malinoski, Darren; Todd, Samuel R.; Slone, D. Sue; Mullins, Richard; Schreiber, Martin.

    In: Archives of Surgery, Vol. 140, No. 11, 11.2005, p. 1122-1125.

    Research output: Contribution to journalArticle

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    AU - Schreiber, Martin

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