Correlation of bioscintigraphy, contrast venography, and iodine-125 fibrinogen uptake test

G. L. DeNardo, S. J. DeNardo, R. F. Carretta, H. G. Bogren, A. L. Jansholt, K. A. Krohn, N. F. Peek

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Abstract

In 40 patients believed to have deep venous thrombosis, bioscintigrams performed with I-123 fibrinogen were available for comparison with either contrast venograms of I-125 fibrinogen uptake tests. If either contrast venography or the fibrinogen uptake test was accepted as a standard for comparison, the accuracy of bioscintigraphic imaging was 90%. Most discrepancies between the procedures could be interpreted as due to heparin treatment, although bioscintigrams often were positive in patients treated with heparin for a short interval of time. Additionally, bioscintigrams provided information to distinguish venous thrombosis from other sources for local accumulation of radioactivity. Bioscintigraphy seems to be a promising noninvasive method for the detection of deep venous thrombosis of the lower extremities.

Original languageEnglish (US)
Pages (from-to)880-883
Number of pages4
JournalClinical Nuclear Medicine
Volume10
Issue number12
DOIs
StatePublished - Dec 1 1985

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    DeNardo, G. L., DeNardo, S. J., Carretta, R. F., Bogren, H. G., Jansholt, A. L., Krohn, K. A., & Peek, N. F. (1985). Correlation of bioscintigraphy, contrast venography, and iodine-125 fibrinogen uptake test. Clinical Nuclear Medicine, 10(12), 880-883. https://doi.org/10.1097/00003072-198512000-00013