Correcting the effects of -20 °C storage and aliquot size on erythrocyte fatty acid content in the women's health initiative

James V. Pottala, Mark A. Espeland, Jason Polreis, Jennifer Robinson, William Harris

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Red blood cell (RBC) fatty acid (FA) patterns have been shown to predict risk for cardiovascular and other chronic diseases. As part of a project analyzing RBC samples from the Women's Health Initiative Memory Study (WHIMS) we observed implausibly low levels of highly unsaturated fatty acids (HUFA) suggestive of degradation. This was hypothesized to be due to short term storage (

Original languageEnglish (US)
Pages (from-to)835-846
Number of pages12
JournalLipids
Volume47
Issue number9
DOIs
StatePublished - Sep 2012
Externally publishedYes

Fingerprint

Women's Health
Blood
Fatty Acids
Erythrocytes
Unsaturated Fatty Acids
Chronic Disease
Cells
Data storage equipment
Degradation

Keywords

  • Erythrocyte
  • Gas chromatography
  • Multiple imputations
  • N-3 Fatty acids
  • N-6 Fatty acids
  • WHIMS

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Organic Chemistry

Cite this

Correcting the effects of -20 °C storage and aliquot size on erythrocyte fatty acid content in the women's health initiative. / Pottala, James V.; Espeland, Mark A.; Polreis, Jason; Robinson, Jennifer; Harris, William.

In: Lipids, Vol. 47, No. 9, 09.2012, p. 835-846.

Research output: Contribution to journalArticle

Pottala, James V. ; Espeland, Mark A. ; Polreis, Jason ; Robinson, Jennifer ; Harris, William. / Correcting the effects of -20 °C storage and aliquot size on erythrocyte fatty acid content in the women's health initiative. In: Lipids. 2012 ; Vol. 47, No. 9. pp. 835-846.
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