Abstract
OBJECTIVE: To determine if ovarian reserve, as measured by day 3 levels Ed 2 and FSH, was different in patients with endometriosis as compared to controls. STUDY DESIGN: Case-control study of 75 women with laparoscopically staged endometriosis and 75 age-matched controls undergoing in vitro fertilization/embryo transfer for male factor infertility. RESULTS: In women with stage III/IV endometriosis (revised American Fertility Society staging), day 3 E 2 and FSH levels were significantly higher than control levels (51.9 pg/mL and 12.6 mIU/mL versus 34.7 pg/mL and 9.7 mIU/mL, P<.03). In contrast, women with stage I/II endometriosis did not differ significantly when compared to controls (36.8 pg/mL and 10.4 mIU/mL versus 34.0 pg/mL and 10.2 mIU/mL). The total group showed significantly higher E 2 levels (41.8 pg/mL versus 34.1 pg/mL, P<.03), but no significant differences in FSH levels were observed. CONCLUSION: These data show that women with stage III/IV endometriosis have relatively diminished ovarian reserve, while this situation is not noted in women with stage I/II endometriosis. This observation is consistent with progressive loss of ovarian reserve in women with increasing stages of endometriosis independent of age.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 7-10 |
| Number of pages | 4 |
| Journal | Journal of Reproductive Medicine for the Obstetrician and Gynecologist |
| Volume | 46 |
| Issue number | 1 |
| State | Published - Feb 13 2001 |
Keywords
- Endometriosis
- Infertility
- Male
- Ovarian reserve
- Ovary
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology