Contribution of angiography to the diagnosis, staging and assessment of radiation and chemotherapy of solid abdominal malignancies in children

Josef Rösch, Robert C. Neerhout, John R. Campbell, Kenneth R. Stevens

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Sequential angiographic studies were done in six children to stage and assess the results of radiation and/or chemotherapy of solid abdominal malignancies: one bilateral Wilms' tumor, two neuroblastomas, two hepatoblastomas and one hepatocarcinoma. Angiography was of value in demonstrating the tumor, its location, extent and vascular characteristics, as well as its regression and recurrence. Wilms' tumor and neuroblastoma responded well to radiation and chemotherapy with substantial decrease in tumor size and regression or disappearance of tumor neovasculature. Resected tumors revealed this to be due to tumor necrosis, hemorrhage and/or cystic degeneration. Hepatoblastoma and hepatocarcinoma did not respond as well to chemotherapy, with only mild decrease in size and neovasculature of the tumor.

Original languageEnglish (US)
Pages (from-to)468-479
Number of pages12
JournalCancer
Volume41
Issue number2
DOIs
StatePublished - Feb 1978

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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