Contrast echocardiography image analysis workstation used to quantify myocardial blood flow using left atrial injection of contrast

D. M. Skyba, A. R. Jayaweera, F. S. Villanueva, S. Ismail, N. C. Goodman, S. Kaul

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    A contrast echocardiography workstation has been developed and has been used to determine whether the myocardial transit rate of microbubbles injected into the left atrium would also correlate with regional myocardial blood flow (RMBF). End diastolic images were analyzed and time intensity plots are automatically derived from the anterior myocardium. It has been found that there is a close linear correlation between myocardial microbubble transit rate and RMBF in the 7 dogs tested (r = 0.83, SEE = 0.14, p < 0.001). A poor correlation was noted between cardiac output and myocardial microbubble transit rate (r=0.43, p=0.14) suggesting that the myocardial transit rate of the microbubbles was not merely reflecting the input function. These findings and image analysis techniques may form the basis of measuring RMBF during myocardial contrast echocardiography following an intravenous injection of contrast.

    Original languageEnglish (US)
    Title of host publication1993 IEEE 19th Annual Northeasrt Bioengineering Conference
    PublisherPubl by IEEE
    Number of pages1
    ISBN (Print)0780309251
    StatePublished - Jan 1 1993
    EventProceedings of the 1993 IEEE 19th Annual Northeast Bioengineering Conference - Newark, NJ, USA
    Duration: Mar 18 1993Mar 19 1993

    Publication series

    NameBioengineering, Proceedings of the Northeast Conference

    Other

    OtherProceedings of the 1993 IEEE 19th Annual Northeast Bioengineering Conference
    CityNewark, NJ, USA
    Period3/18/933/19/93

    ASJC Scopus subject areas

    • Bioengineering

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  • Cite this

    Skyba, D. M., Jayaweera, A. R., Villanueva, F. S., Ismail, S., Goodman, N. C., & Kaul, S. (1993). Contrast echocardiography image analysis workstation used to quantify myocardial blood flow using left atrial injection of contrast. In 1993 IEEE 19th Annual Northeasrt Bioengineering Conference (Bioengineering, Proceedings of the Northeast Conference). Publ by IEEE.