Consumption of caffeinated products and cardiac ectopy

Shalini Dixit, Phyllis K. Stein, Thomas Dewland, Jonathan W. Dukes, Eric Vittinghoff, Susan R. Heckbert, Gregory M. Marcus

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background-Premature cardiac contractions are associated with increased morbidity and mortality. Though experts associate premature atrial contractions (PACs) and premature ventricular contractions (PVCs) with caffeine, there are no data to support this relationship in the general population. As certain caffeinated products may have cardiovascular benefits, recommendations against them may be detrimental. Methods and Results-We studied Cardiovascular Health Study participants with a baseline food frequency assessment, 24- hour ambulatory electrocardiography (Holter) monitoring, and without persistent atrial fibrillation. Frequencies of habitual coffee, tea, and chocolate consumption were assessed using a picture-sort food frequency survey. The main outcomes were PACs/h and PVCs/hour. Among 1388 participants (46% male, mean age 72 years), 840 (61%) consumed ≥1 caffeinated product per day. The median numbers of PACs and PVCs/h and interquartile ranges were 3 (1-12) and 1 (0-7), respectively. There were no differences in the number of PACs or PVCs/h across levels of coffee, tea, and chocolate consumption. After adjustment for potential confounders, more frequent consumption of these products was not associated with ectopy. In examining combined dietary intake of coffee, tea, and chocolate as a continuous measure, no relationships were observed after multivariable adjustment: 0.48% fewer PACs/h (95% CI -4.60 to 3.64) and 2.87% fewer PVCs/h (95% CI -8.18 to 2.43) per 1-serving/week increase in consumption. Conclusions-In the largest study to evaluate dietary patterns and quantify cardiac ectopy using 24-hour Holter monitoring, we found no relationship between chronic consumption of caffeinated products and ectopy.

Original languageEnglish (US)
Article numbere002503
JournalJournal of the American Heart Association
Volume5
Issue number1
DOIs
StatePublished - 2016

Fingerprint

Atrial Premature Complexes
Ventricular Premature Complexes
Coffee
Tea
Ambulatory Electrocardiography
Food
Caffeine
Atrial Fibrillation
Morbidity
Mortality
Health
Population
Chocolate

Keywords

  • Arrhythmia
  • Diet
  • Electrophysiology
  • Epidemiology

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Dixit, S., Stein, P. K., Dewland, T., Dukes, J. W., Vittinghoff, E., Heckbert, S. R., & Marcus, G. M. (2016). Consumption of caffeinated products and cardiac ectopy. Journal of the American Heart Association, 5(1), [e002503]. https://doi.org/10.1161/JAHA.115.002503

Consumption of caffeinated products and cardiac ectopy. / Dixit, Shalini; Stein, Phyllis K.; Dewland, Thomas; Dukes, Jonathan W.; Vittinghoff, Eric; Heckbert, Susan R.; Marcus, Gregory M.

In: Journal of the American Heart Association, Vol. 5, No. 1, e002503, 2016.

Research output: Contribution to journalArticle

Dixit, S, Stein, PK, Dewland, T, Dukes, JW, Vittinghoff, E, Heckbert, SR & Marcus, GM 2016, 'Consumption of caffeinated products and cardiac ectopy', Journal of the American Heart Association, vol. 5, no. 1, e002503. https://doi.org/10.1161/JAHA.115.002503
Dixit, Shalini ; Stein, Phyllis K. ; Dewland, Thomas ; Dukes, Jonathan W. ; Vittinghoff, Eric ; Heckbert, Susan R. ; Marcus, Gregory M. / Consumption of caffeinated products and cardiac ectopy. In: Journal of the American Heart Association. 2016 ; Vol. 5, No. 1.
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abstract = "Background-Premature cardiac contractions are associated with increased morbidity and mortality. Though experts associate premature atrial contractions (PACs) and premature ventricular contractions (PVCs) with caffeine, there are no data to support this relationship in the general population. As certain caffeinated products may have cardiovascular benefits, recommendations against them may be detrimental. Methods and Results-We studied Cardiovascular Health Study participants with a baseline food frequency assessment, 24- hour ambulatory electrocardiography (Holter) monitoring, and without persistent atrial fibrillation. Frequencies of habitual coffee, tea, and chocolate consumption were assessed using a picture-sort food frequency survey. The main outcomes were PACs/h and PVCs/hour. Among 1388 participants (46{\%} male, mean age 72 years), 840 (61{\%}) consumed ≥1 caffeinated product per day. The median numbers of PACs and PVCs/h and interquartile ranges were 3 (1-12) and 1 (0-7), respectively. There were no differences in the number of PACs or PVCs/h across levels of coffee, tea, and chocolate consumption. After adjustment for potential confounders, more frequent consumption of these products was not associated with ectopy. In examining combined dietary intake of coffee, tea, and chocolate as a continuous measure, no relationships were observed after multivariable adjustment: 0.48{\%} fewer PACs/h (95{\%} CI -4.60 to 3.64) and 2.87{\%} fewer PVCs/h (95{\%} CI -8.18 to 2.43) per 1-serving/week increase in consumption. Conclusions-In the largest study to evaluate dietary patterns and quantify cardiac ectopy using 24-hour Holter monitoring, we found no relationship between chronic consumption of caffeinated products and ectopy.",
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AB - Background-Premature cardiac contractions are associated with increased morbidity and mortality. Though experts associate premature atrial contractions (PACs) and premature ventricular contractions (PVCs) with caffeine, there are no data to support this relationship in the general population. As certain caffeinated products may have cardiovascular benefits, recommendations against them may be detrimental. Methods and Results-We studied Cardiovascular Health Study participants with a baseline food frequency assessment, 24- hour ambulatory electrocardiography (Holter) monitoring, and without persistent atrial fibrillation. Frequencies of habitual coffee, tea, and chocolate consumption were assessed using a picture-sort food frequency survey. The main outcomes were PACs/h and PVCs/hour. Among 1388 participants (46% male, mean age 72 years), 840 (61%) consumed ≥1 caffeinated product per day. The median numbers of PACs and PVCs/h and interquartile ranges were 3 (1-12) and 1 (0-7), respectively. There were no differences in the number of PACs or PVCs/h across levels of coffee, tea, and chocolate consumption. After adjustment for potential confounders, more frequent consumption of these products was not associated with ectopy. In examining combined dietary intake of coffee, tea, and chocolate as a continuous measure, no relationships were observed after multivariable adjustment: 0.48% fewer PACs/h (95% CI -4.60 to 3.64) and 2.87% fewer PVCs/h (95% CI -8.18 to 2.43) per 1-serving/week increase in consumption. Conclusions-In the largest study to evaluate dietary patterns and quantify cardiac ectopy using 24-hour Holter monitoring, we found no relationship between chronic consumption of caffeinated products and ectopy.

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