Consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer: From concept to reality

Jose Serrano, Dana Andersen, Christopher E. Forsmark, Stephen J. Pandol, Ziding Feng, Sudhir Srivastava, Jo Ann S. Rinaudo

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Research progress in diseases of the exocrine pancreas [chronic pancreatitis (CP), pancreatogenic diabetes mellitus, and pancreatic cancer] has been hampered by the disorders' heterogeneity, the limitations of previous small cross-sectional studies, the inability to safely obtain pancreatic tissue for study, and the lack of structured epidemiology tools, genetic testing, and biomarker development. Mechanism-based research of these diseases has suffered from the lack of systematically collected clinical measures in longitudinal cohort studies linked with biospecimens. Given the increasing incidence and prevalence of CP and its association to the development of pancreatic cancer, its complications, high mortality rate, and associated health care cost, the National Institute for Diabetes and Digestive and Kidney Diseases and the National Cancer Institute funded the Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer to identify research gaps and foster multidisciplinary collaborations to better diagnose, characterize, and manage CP and its sequelae. The CPDPC structure, governance, and research objectives are described in this article. Studies undertaken by the CPDPC are described in other articles in this journal's issue.

Original languageEnglish (US)
Pages (from-to)1208-1212
Number of pages5
JournalPancreas
Volume47
Issue number10
DOIs
StatePublished - Nov 1 2018
Externally publishedYes

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Keywords

  • chronic pancreatitis
  • Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer
  • INSPPIRE
  • new-onset diabetes (NOD)
  • pancreatic cancer
  • PROCEED Study

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

Cite this

Serrano, J., Andersen, D., Forsmark, C. E., Pandol, S. J., Feng, Z., Srivastava, S., & Rinaudo, J. A. S. (2018). Consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer: From concept to reality. Pancreas, 47(10), 1208-1212. https://doi.org/10.1097/MPA.0000000000001167