Consensus-based recommendations for optical coherence tomography angiography reporting in uveitis

Francesco Pichi, Ester Carreño, Carlos Pavesio, Alastair K. Denniston, Dilraj S. Grewal, Gabor Deak, Moncef Khairallah, Matilde Ruiz-Cruz, Joao Rafael de Oliveira Dias, Alfredo Adan, Tomas Burke, Alessandro Invernizzi, Ariel Schlaen, Meng Tian, Aniruddha Kishandutt Agarwal, William R. Tucker, H. Nida Sen, Phoebe Lin, Lyndell L. Lim, Kathryn L. PeppleMarion R. Munk

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Background/aims To establish a consensus in the nomenclature for reporting optical coherence tomography angiography (OCTA findings in uveitis. Methods The modified Delphi process consisted of two rounds of electronic questionnaires, followed by a face-to-face meeting conducted virtually. Twenty-one items were included for discussion. The three main areas of discussion were: wide field OCTA (WF-OCTA), nomenclature of OCTA findings and OCTA signal attenuation assessment and measurement. Seventeen specialists in uveitis and retinal imaging were selected by the executive committee to constitute the OCTA nomenclature in Uveitis Delphi Study Group. The study endpoint was defined by the degree of consensus for each question:’strong consensus’ was defined as >90% agreement,’consensus’ as 85%–90% and’near consensus’ as >80% but <85%. Results There was a strong consensus to apply the term’wide field’ to OCTA images measuring over 70° of field of view, to use the terms’flow deficit’ and’non-detectable flow signal’ to describe abnormal OCTA flow signal secondary to slow flow and to vessels displacement respectively, to use the terms’loose’ and’dense’ to describe the appearance of inflammatory choroidal neovascularisation, and to use the percentage of flow signal decrease to measure OCTA ischaemia with a threshold greater than or equal to 30% as a’large area’. Conclusions This study sets up consensus recommendations for reporting OCTA findings in uveitis by an expert panel, which may prove suitable for use in routine clinical care and clinical trials.

Original languageEnglish (US)
Pages (from-to)959-965
Number of pages7
JournalBritish Journal of Ophthalmology
Volume107
Issue number7
DOIs
StatePublished - 2023

ASJC Scopus subject areas

  • Sensory Systems
  • Cellular and Molecular Neuroscience
  • Ophthalmology

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