Computerized acoustic cardiography correlates with echocardiography and invasive haemodynamics after percutaneous transvenous mitral commissurotomy

S. Gupta, N. Gupta, P. Arand, A. D. Michaels

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    Background:Rheumatic mitral stenosis severity has been assessed by the systolic time interval between the QRS onset and the first heart sound (QS1) by phonocardiography. We hypothesized that non-invasive computerized acoustic cardiography could evaluate mitral stenosis severity compared with echocardiography and invasive haemodynamics in patients undergoing percutaneous transvenous mitral commissurotomy (PTMC). Methods:27 patients underwent computerized acoustic cardiography, echocardiography, and invasive haemodynamic measurements prior to and after PTMC. Results:The mean age was 31±10 years, and 21 (78%) were female. By echocardiography, mitral valve area increased from 0.82±0.14 to 1.50±0.24 cm2 (p<0.0001). The QS1 interval decreased from 101.7±12.9 to 93.2±9.2ms (p<0.0001). The change in the QS1 interval correlated with the change in mitral valve area by echocardiography (p=0.037), right ventricular systolic pressure (p<0.0001), and the invasive mitral valve gradient (p=0.076). Conclusions:Acoustic cardiography may be used as an adjunctive non-invasive diagnostic tool to assess mitral stenosis severity.

    Original languageEnglish (US)
    Pages (from-to)59-64
    Number of pages6
    JournalJournal of Medical Engineering and Technology
    Issue number1
    StatePublished - Jan 1 2011



    • Acoustic cardiography
    • Echocardiography
    • Haemodynamics
    • Heart sounds
    • Rheumatic mitral stenosis

    ASJC Scopus subject areas

    • Biomedical Engineering

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