Computed tomography-based high-risk coronary plaque score to predict acute coronary syndrome among patients with acute chest pain - Results from the ROMICAT II trial

Maros Ferencik, Thomas Mayrhofer, Stefan B. Puchner, Michael T. Lu, Pal Maurovich-Horvat, Ting Liu, Khristine Ghemigian, Pieter Kitslaar, Alexander Broersen, Fabian Bamberg, Quynh A. Truong, Christopher L. Schlett, Udo Hoffmann

    Research output: Contribution to journalArticle

    33 Scopus citations

    Abstract

    Background: Coronary computed tomography angiography (CTA) can be used to detect and quantitatively assess high-risk plaque features. Objective: To validate the ROMICAT score, which was derived using semi-automated quantitative measurements of high-risk plaque features, for the prediction of ACS. Material and methods: We performed quantitative plaque analysis in 260 patients who presented to the emergency department with suspected ACS in the ROMICAT II trial. The readers used a semi-automated software (QAngio, Medis medical imaging systems BV) to measure high-risk plaque features (volume of

    Original languageEnglish (US)
    Pages (from-to)538-545
    Number of pages8
    JournalJournal of Cardiovascular Computed Tomography
    Volume9
    Issue number6
    DOIs
    StatePublished - Nov 1 2015

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    Keywords

    • Acute chest pain
    • Acute coronary syndrome
    • Coronary atherosclerotic plaque
    • Coronary computed tomography angiography
    • Risk score

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine
    • Radiology Nuclear Medicine and imaging

    Cite this

    Ferencik, M., Mayrhofer, T., Puchner, S. B., Lu, M. T., Maurovich-Horvat, P., Liu, T., Ghemigian, K., Kitslaar, P., Broersen, A., Bamberg, F., Truong, Q. A., Schlett, C. L., & Hoffmann, U. (2015). Computed tomography-based high-risk coronary plaque score to predict acute coronary syndrome among patients with acute chest pain - Results from the ROMICAT II trial. Journal of Cardiovascular Computed Tomography, 9(6), 538-545. https://doi.org/10.1016/j.jcct.2015.07.003