Complex-trait genetics: Emergence of multivariate strategies

Tamara J. Phillips, John K. Belknap

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


Complex traits, including many disease-related traits, are influenced by multiple genes. Bivariate approaches that associate one gene with one trait are yielding to multivariate methods to synthesize the effects of multiple genes, integrate results across independent studies, and aid in the identification of coordinated pathways and interactions between loci.

Original languageEnglish (US)
Pages (from-to)478-485
Number of pages8
JournalNature Reviews Neuroscience
Issue number6
StatePublished - Jun 2002

ASJC Scopus subject areas

  • Neuroscience(all)


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