Complex fetal disorders

Effect of MR imaging on management - Preliminary clinical experience

Fergus Coakley, Hedvig Hricak, Roy A. Filly, Anthony J. Barkovich, Michael R. Harrison

Research output: Contribution to journalArticle

105 Citations (Scopus)

Abstract

PURPOSE: To determine the effect of magnetic resonance (MR) imaging findings on management of complex fetal disorders. MATERIALS AND METHODS: MR imaging of the fetus was performed in 25 consecutive pregnant patients referred because of possible complex fetal disorders suspected on the basis of ultrasonographic (US) findings. Spoiled gradient-echo and single-shot rapid acquisition with relaxation enhancement MR imaging were performed in multiple planes anatomic to the fetus during maternal breath holding. RESULTS: In the fetuses in 24 of 25 women, MR studies were technically satisfactory. MR imaging directly influenced fetal care in four (17%) of 24 cases by demonstrating congenital high airway obstruction syndrome, congenital hemochromatosis, unilateral cerebellar deficiency in association with congenital diaphragmatic hernia, and severe facial disfigurement due to a giant anterior neck mass. In eight (33%) cases, MR imaging provided supplementary findings, but did not affect fetal care. In 12 (50%) cases, MR imaging results confirmed US findings. CONCLUSION: In cases of complex fetal disorders, MR imaging results can be used to supplement or confirm US findings and may directly affect management.

Original languageEnglish (US)
Pages (from-to)691-696
Number of pages6
JournalRadiology
Volume213
Issue number3
StatePublished - Dec 1999
Externally publishedYes

Fingerprint

Magnetic Resonance Imaging
Fetus
Breath Holding
Hemochromatosis
Airway Obstruction
Neck
Magnetic Resonance Spectroscopy
Mothers

Keywords

  • Brain, hydrocephalus
  • Central nervous system
  • Fetus
  • Fetus, gastrointestinal tract
  • Fetus, MR
  • Fetus, respiratory system
  • Fetus, US
  • Hemochromatosis
  • Hernia, diaphragmatic
  • Lung, congenital malformation

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Coakley, F., Hricak, H., Filly, R. A., Barkovich, A. J., & Harrison, M. R. (1999). Complex fetal disorders: Effect of MR imaging on management - Preliminary clinical experience. Radiology, 213(3), 691-696.

Complex fetal disorders : Effect of MR imaging on management - Preliminary clinical experience. / Coakley, Fergus; Hricak, Hedvig; Filly, Roy A.; Barkovich, Anthony J.; Harrison, Michael R.

In: Radiology, Vol. 213, No. 3, 12.1999, p. 691-696.

Research output: Contribution to journalArticle

Coakley, F, Hricak, H, Filly, RA, Barkovich, AJ & Harrison, MR 1999, 'Complex fetal disorders: Effect of MR imaging on management - Preliminary clinical experience', Radiology, vol. 213, no. 3, pp. 691-696.
Coakley F, Hricak H, Filly RA, Barkovich AJ, Harrison MR. Complex fetal disorders: Effect of MR imaging on management - Preliminary clinical experience. Radiology. 1999 Dec;213(3):691-696.
Coakley, Fergus ; Hricak, Hedvig ; Filly, Roy A. ; Barkovich, Anthony J. ; Harrison, Michael R. / Complex fetal disorders : Effect of MR imaging on management - Preliminary clinical experience. In: Radiology. 1999 ; Vol. 213, No. 3. pp. 691-696.
@article{c56fce214920425ca94a62d6e96fb653,
title = "Complex fetal disorders: Effect of MR imaging on management - Preliminary clinical experience",
abstract = "PURPOSE: To determine the effect of magnetic resonance (MR) imaging findings on management of complex fetal disorders. MATERIALS AND METHODS: MR imaging of the fetus was performed in 25 consecutive pregnant patients referred because of possible complex fetal disorders suspected on the basis of ultrasonographic (US) findings. Spoiled gradient-echo and single-shot rapid acquisition with relaxation enhancement MR imaging were performed in multiple planes anatomic to the fetus during maternal breath holding. RESULTS: In the fetuses in 24 of 25 women, MR studies were technically satisfactory. MR imaging directly influenced fetal care in four (17{\%}) of 24 cases by demonstrating congenital high airway obstruction syndrome, congenital hemochromatosis, unilateral cerebellar deficiency in association with congenital diaphragmatic hernia, and severe facial disfigurement due to a giant anterior neck mass. In eight (33{\%}) cases, MR imaging provided supplementary findings, but did not affect fetal care. In 12 (50{\%}) cases, MR imaging results confirmed US findings. CONCLUSION: In cases of complex fetal disorders, MR imaging results can be used to supplement or confirm US findings and may directly affect management.",
keywords = "Brain, hydrocephalus, Central nervous system, Fetus, Fetus, gastrointestinal tract, Fetus, MR, Fetus, respiratory system, Fetus, US, Hemochromatosis, Hernia, diaphragmatic, Lung, congenital malformation",
author = "Fergus Coakley and Hedvig Hricak and Filly, {Roy A.} and Barkovich, {Anthony J.} and Harrison, {Michael R.}",
year = "1999",
month = "12",
language = "English (US)",
volume = "213",
pages = "691--696",
journal = "Radiology",
issn = "0033-8419",
publisher = "Radiological Society of North America Inc.",
number = "3",

}

TY - JOUR

T1 - Complex fetal disorders

T2 - Effect of MR imaging on management - Preliminary clinical experience

AU - Coakley, Fergus

AU - Hricak, Hedvig

AU - Filly, Roy A.

AU - Barkovich, Anthony J.

AU - Harrison, Michael R.

PY - 1999/12

Y1 - 1999/12

N2 - PURPOSE: To determine the effect of magnetic resonance (MR) imaging findings on management of complex fetal disorders. MATERIALS AND METHODS: MR imaging of the fetus was performed in 25 consecutive pregnant patients referred because of possible complex fetal disorders suspected on the basis of ultrasonographic (US) findings. Spoiled gradient-echo and single-shot rapid acquisition with relaxation enhancement MR imaging were performed in multiple planes anatomic to the fetus during maternal breath holding. RESULTS: In the fetuses in 24 of 25 women, MR studies were technically satisfactory. MR imaging directly influenced fetal care in four (17%) of 24 cases by demonstrating congenital high airway obstruction syndrome, congenital hemochromatosis, unilateral cerebellar deficiency in association with congenital diaphragmatic hernia, and severe facial disfigurement due to a giant anterior neck mass. In eight (33%) cases, MR imaging provided supplementary findings, but did not affect fetal care. In 12 (50%) cases, MR imaging results confirmed US findings. CONCLUSION: In cases of complex fetal disorders, MR imaging results can be used to supplement or confirm US findings and may directly affect management.

AB - PURPOSE: To determine the effect of magnetic resonance (MR) imaging findings on management of complex fetal disorders. MATERIALS AND METHODS: MR imaging of the fetus was performed in 25 consecutive pregnant patients referred because of possible complex fetal disorders suspected on the basis of ultrasonographic (US) findings. Spoiled gradient-echo and single-shot rapid acquisition with relaxation enhancement MR imaging were performed in multiple planes anatomic to the fetus during maternal breath holding. RESULTS: In the fetuses in 24 of 25 women, MR studies were technically satisfactory. MR imaging directly influenced fetal care in four (17%) of 24 cases by demonstrating congenital high airway obstruction syndrome, congenital hemochromatosis, unilateral cerebellar deficiency in association with congenital diaphragmatic hernia, and severe facial disfigurement due to a giant anterior neck mass. In eight (33%) cases, MR imaging provided supplementary findings, but did not affect fetal care. In 12 (50%) cases, MR imaging results confirmed US findings. CONCLUSION: In cases of complex fetal disorders, MR imaging results can be used to supplement or confirm US findings and may directly affect management.

KW - Brain, hydrocephalus

KW - Central nervous system

KW - Fetus

KW - Fetus, gastrointestinal tract

KW - Fetus, MR

KW - Fetus, respiratory system

KW - Fetus, US

KW - Hemochromatosis

KW - Hernia, diaphragmatic

KW - Lung, congenital malformation

UR - http://www.scopus.com/inward/record.url?scp=0032750912&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032750912&partnerID=8YFLogxK

M3 - Article

VL - 213

SP - 691

EP - 696

JO - Radiology

JF - Radiology

SN - 0033-8419

IS - 3

ER -