Complete nucleotide sequence of a chicken H2b histone gene

David Grandy, J. D. Engel, J. B. Dodgson

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The complete nucleotide sequence of a chicken H2b histone gene has been determined along with extensive flanking sequence both 5' and 3' from the gene. This H2b gene was isolated on λ Charon 4A-chicken DNA recombinant in which it is closely linked to two H3 histone genes. The H2b histone gene predicts a chicken H2b histone protein sequence differing in 5 of 125 amino acids from the sequence of a calf thymus H2b histone. The gene is uninterrupted and is flanked by several consensus sequences seen in many other eucaryotic genes. In particular, unlike many other histone genes it contains a 3'-AATAAA sequence usually associated with genes coding for polyadenylated mRNA.

Original languageEnglish (US)
Pages (from-to)8577-8580
Number of pages4
JournalJournal of Biological Chemistry
Volume257
Issue number15
StatePublished - 1982
Externally publishedYes

Fingerprint

Histones
Chickens
Nucleotides
Genes
Pluto
3' Flanking Region
Thymus
Recombinant DNA
5' Flanking Region
Consensus Sequence
Thymus Gland
Amino Acid Sequence
Amino Acids
Messenger RNA

ASJC Scopus subject areas

  • Biochemistry

Cite this

Grandy, D., Engel, J. D., & Dodgson, J. B. (1982). Complete nucleotide sequence of a chicken H2b histone gene. Journal of Biological Chemistry, 257(15), 8577-8580.

Complete nucleotide sequence of a chicken H2b histone gene. / Grandy, David; Engel, J. D.; Dodgson, J. B.

In: Journal of Biological Chemistry, Vol. 257, No. 15, 1982, p. 8577-8580.

Research output: Contribution to journalArticle

Grandy, D, Engel, JD & Dodgson, JB 1982, 'Complete nucleotide sequence of a chicken H2b histone gene', Journal of Biological Chemistry, vol. 257, no. 15, pp. 8577-8580.
Grandy, David ; Engel, J. D. ; Dodgson, J. B. / Complete nucleotide sequence of a chicken H2b histone gene. In: Journal of Biological Chemistry. 1982 ; Vol. 257, No. 15. pp. 8577-8580.
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