Complete nucleotide sequence of a chicken H2b histone gene

D. K. Grandy, J. D. Engel, J. B. Dodgson

    Research output: Contribution to journalArticle

    24 Scopus citations

    Abstract

    The complete nucleotide sequence of a chicken H2b histone gene has been determined along with extensive flanking sequence both 5' and 3' from the gene. This H2b gene was isolated on λ Charon 4A-chicken DNA recombinant in which it is closely linked to two H3 histone genes. The H2b histone gene predicts a chicken H2b histone protein sequence differing in 5 of 125 amino acids from the sequence of a calf thymus H2b histone. The gene is uninterrupted and is flanked by several consensus sequences seen in many other eucaryotic genes. In particular, unlike many other histone genes it contains a 3'-AATAAA sequence usually associated with genes coding for polyadenylated mRNA.

    Original languageEnglish (US)
    Pages (from-to)8577-8580
    Number of pages4
    JournalJournal of Biological Chemistry
    Volume257
    Issue number15
    StatePublished - Dec 1 1982

    ASJC Scopus subject areas

    • Biochemistry
    • Molecular Biology
    • Cell Biology

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  • Cite this

    Grandy, D. K., Engel, J. D., & Dodgson, J. B. (1982). Complete nucleotide sequence of a chicken H2b histone gene. Journal of Biological Chemistry, 257(15), 8577-8580.