Complete nucleotide sequence of a chicken H2b histone gene

D. K. Grandy, J. D. Engel, J. B. Dodgson

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations


    The complete nucleotide sequence of a chicken H2b histone gene has been determined along with extensive flanking sequence both 5' and 3' from the gene. This H2b gene was isolated on λ Charon 4A-chicken DNA recombinant in which it is closely linked to two H3 histone genes. The H2b histone gene predicts a chicken H2b histone protein sequence differing in 5 of 125 amino acids from the sequence of a calf thymus H2b histone. The gene is uninterrupted and is flanked by several consensus sequences seen in many other eucaryotic genes. In particular, unlike many other histone genes it contains a 3'-AATAAA sequence usually associated with genes coding for polyadenylated mRNA.

    Original languageEnglish (US)
    Pages (from-to)8577-8580
    Number of pages4
    JournalJournal of Biological Chemistry
    Issue number15
    StatePublished - 1982

    ASJC Scopus subject areas

    • Biochemistry
    • Molecular Biology
    • Cell Biology


    Dive into the research topics of 'Complete nucleotide sequence of a chicken H2b histone gene'. Together they form a unique fingerprint.

    Cite this