Comparison of the Antimicrobial Efficacy of 1.3% NaOCl/BioPure MTAD to 5.25% NaOCl/15% EDTA for Root Canal Irrigation

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

The purpose of this study was to compare the antimicrobial efficacy of 1.3% NaOCl/BioPure MTAD to 5.25% NaOCl/15% EDTA for root canal irrigation. Twenty-six bilaterally matched pairs of human teeth were collected. The teeth were incubated with Enterococcus faecalis for 4 weeks. The teeth were divided into two experimental groups and one positive control group. The canals were instrumented and irrigated with either 5.25% NaOCl/15% EDTA or 1.3% NaOCl/BioPure MTAD. Bacterial samples were collected after instrumentation/irrigation and after additional canal enlargement. Statistical analysis of the data using the Wilcoxon Signed Rank test showed significant differences between the experimental groups. The first bacterial samples revealed growth in 0 of 20 samples with 5.25% NaOCl/15% EDTA irrigation and in 8 of 20 samples with 1.3% NaOCl/BioPure MTAD irrigation. Samples taken after additional canal enlargement revealed growth in 0 of 20 samples in 5.25% NaOCl/15% EDTA and in 10 of 20 samples in 1.3% NaOCl/BioPure MTAD group. This investigation showed consistent disinfection of infected root canals with 5.25% NaOCl/15% EDTA. The combination of 1.3% NaOCl/BioPure MTAD left nearly 50% of the canals contaminated with E. faecalis.

Original languageEnglish (US)
Pages (from-to)48-51
Number of pages4
JournalJournal of Endodontics
Volume33
Issue number1
DOIs
StatePublished - Jan 2007

Fingerprint

Dental Pulp Cavity
Edetic Acid
Tooth
Enterococcus faecalis
Statistical Data Interpretation
Disinfection
Growth
Nonparametric Statistics
MTAD (intracanal irrigant)
Control Groups

Keywords

  • MTAD
  • root canal irrigation
  • sodium hypochlorite

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

@article{0a7abcd001fc4016aff18a051fd0b8e9,
title = "Comparison of the Antimicrobial Efficacy of 1.3{\%} NaOCl/BioPure MTAD to 5.25{\%} NaOCl/15{\%} EDTA for Root Canal Irrigation",
abstract = "The purpose of this study was to compare the antimicrobial efficacy of 1.3{\%} NaOCl/BioPure MTAD to 5.25{\%} NaOCl/15{\%} EDTA for root canal irrigation. Twenty-six bilaterally matched pairs of human teeth were collected. The teeth were incubated with Enterococcus faecalis for 4 weeks. The teeth were divided into two experimental groups and one positive control group. The canals were instrumented and irrigated with either 5.25{\%} NaOCl/15{\%} EDTA or 1.3{\%} NaOCl/BioPure MTAD. Bacterial samples were collected after instrumentation/irrigation and after additional canal enlargement. Statistical analysis of the data using the Wilcoxon Signed Rank test showed significant differences between the experimental groups. The first bacterial samples revealed growth in 0 of 20 samples with 5.25{\%} NaOCl/15{\%} EDTA irrigation and in 8 of 20 samples with 1.3{\%} NaOCl/BioPure MTAD irrigation. Samples taken after additional canal enlargement revealed growth in 0 of 20 samples in 5.25{\%} NaOCl/15{\%} EDTA and in 10 of 20 samples in 1.3{\%} NaOCl/BioPure MTAD group. This investigation showed consistent disinfection of infected root canals with 5.25{\%} NaOCl/15{\%} EDTA. The combination of 1.3{\%} NaOCl/BioPure MTAD left nearly 50{\%} of the canals contaminated with E. faecalis.",
keywords = "MTAD, root canal irrigation, sodium hypochlorite",
author = "Baumgartner, {John (Craig)} and Stephen Johal and Marshall, {J (Gordon)}",
year = "2007",
month = "1",
doi = "10.1016/j.joen.2006.08.007",
language = "English (US)",
volume = "33",
pages = "48--51",
journal = "Journal of Endodontics",
issn = "0099-2399",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Comparison of the Antimicrobial Efficacy of 1.3% NaOCl/BioPure MTAD to 5.25% NaOCl/15% EDTA for Root Canal Irrigation

AU - Baumgartner, John (Craig)

AU - Johal, Stephen

AU - Marshall, J (Gordon)

PY - 2007/1

Y1 - 2007/1

N2 - The purpose of this study was to compare the antimicrobial efficacy of 1.3% NaOCl/BioPure MTAD to 5.25% NaOCl/15% EDTA for root canal irrigation. Twenty-six bilaterally matched pairs of human teeth were collected. The teeth were incubated with Enterococcus faecalis for 4 weeks. The teeth were divided into two experimental groups and one positive control group. The canals were instrumented and irrigated with either 5.25% NaOCl/15% EDTA or 1.3% NaOCl/BioPure MTAD. Bacterial samples were collected after instrumentation/irrigation and after additional canal enlargement. Statistical analysis of the data using the Wilcoxon Signed Rank test showed significant differences between the experimental groups. The first bacterial samples revealed growth in 0 of 20 samples with 5.25% NaOCl/15% EDTA irrigation and in 8 of 20 samples with 1.3% NaOCl/BioPure MTAD irrigation. Samples taken after additional canal enlargement revealed growth in 0 of 20 samples in 5.25% NaOCl/15% EDTA and in 10 of 20 samples in 1.3% NaOCl/BioPure MTAD group. This investigation showed consistent disinfection of infected root canals with 5.25% NaOCl/15% EDTA. The combination of 1.3% NaOCl/BioPure MTAD left nearly 50% of the canals contaminated with E. faecalis.

AB - The purpose of this study was to compare the antimicrobial efficacy of 1.3% NaOCl/BioPure MTAD to 5.25% NaOCl/15% EDTA for root canal irrigation. Twenty-six bilaterally matched pairs of human teeth were collected. The teeth were incubated with Enterococcus faecalis for 4 weeks. The teeth were divided into two experimental groups and one positive control group. The canals were instrumented and irrigated with either 5.25% NaOCl/15% EDTA or 1.3% NaOCl/BioPure MTAD. Bacterial samples were collected after instrumentation/irrigation and after additional canal enlargement. Statistical analysis of the data using the Wilcoxon Signed Rank test showed significant differences between the experimental groups. The first bacterial samples revealed growth in 0 of 20 samples with 5.25% NaOCl/15% EDTA irrigation and in 8 of 20 samples with 1.3% NaOCl/BioPure MTAD irrigation. Samples taken after additional canal enlargement revealed growth in 0 of 20 samples in 5.25% NaOCl/15% EDTA and in 10 of 20 samples in 1.3% NaOCl/BioPure MTAD group. This investigation showed consistent disinfection of infected root canals with 5.25% NaOCl/15% EDTA. The combination of 1.3% NaOCl/BioPure MTAD left nearly 50% of the canals contaminated with E. faecalis.

KW - MTAD

KW - root canal irrigation

KW - sodium hypochlorite

UR - http://www.scopus.com/inward/record.url?scp=33846238997&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846238997&partnerID=8YFLogxK

U2 - 10.1016/j.joen.2006.08.007

DO - 10.1016/j.joen.2006.08.007

M3 - Article

C2 - 17185130

AN - SCOPUS:33846238997

VL - 33

SP - 48

EP - 51

JO - Journal of Endodontics

JF - Journal of Endodontics

SN - 0099-2399

IS - 1

ER -