TY - JOUR
T1 - Comparison of plaque- and flow cytometry-based methods for measuring dengue virus neutralization
AU - Kraus, Annette A.
AU - Messer, William
AU - Haymore, Laura B.
AU - De Silva, Aravinda M.
PY - 2007/11
Y1 - 2007/11
N2 - As dengue vaccines enter clinical trials, there is a need for rapid and quantitative assays to measure neutralization. We have developed flow-based neutralization assays which generated results similar to those generated by the established, plaque reduction neutralization test. The flow assays are an improvement, as they use human cells and allow for high-throughput screening.
AB - As dengue vaccines enter clinical trials, there is a need for rapid and quantitative assays to measure neutralization. We have developed flow-based neutralization assays which generated results similar to those generated by the established, plaque reduction neutralization test. The flow assays are an improvement, as they use human cells and allow for high-throughput screening.
UR - http://www.scopus.com/inward/record.url?scp=36349025968&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=36349025968&partnerID=8YFLogxK
U2 - 10.1128/JCM.00827-07
DO - 10.1128/JCM.00827-07
M3 - Article
C2 - 17804661
AN - SCOPUS:36349025968
SN - 0095-1137
VL - 45
SP - 3777
EP - 3780
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
IS - 11
ER -