Comparison of Multidetector Computed Tomography and Two-Dimensional Transthoracic Echocardiography for Left Ventricular Assessment in Patients With Heart Failure

Javed Butler, Michael D. Shapiro, Davindar Jassal, Tomas Neilan, John Nichols, Maros Ferencik, Thomas J. Brady, Udo Hoffmann, Ricardo C. Cury

    Research output: Contribution to journalArticle

    45 Scopus citations

    Abstract

    Along with coronary evaluation, 64-slice multidetector computed tomography (MDCT) permits comprehensive assessment of left ventricular (LV) anatomy and function; however, how it compares with 2-dimensional transthoracic echocardiography (TTE) in patients with heart failure (HF) is not known. In this study, we compared 25 patients with ejection fractions of <45% who underwent TTE and MDCT. The global ejection fraction by TTE versus MDCT was 36 ± 8% versus 38 ± 12% (r = 0.67, p = NS). The mean LV end-diastolic and end-systolic diameters by TTE and MDCT were 56 ± 8 and 46 ± 9 mm and 58 ± 12 and 47 ± 11 mm, respectively (r = 0.71 and 0.77, respectively, both p >0.20). The mean lateral and septal wall thicknesses by TTE and MDCT were 10 ± 1.4 and 11 ± 1.5 mm and 10 ± 1.3 and 10 ± 1.4 mm (r = 0.77 and 0.76, respectively, both p >0.20). The mean LV end-diastolic and end-systolic volumes and stroke volume by TTE and MDCT were 123 ± 45, 78 ± 31, and 44 ± 21 ml and 140 ± 58, 92 ± 43, and 48 ± 24 ml, respectively (r = 0.62, 0.67, and 0.60, respectively, all p >0.20). The regional wall motion assessment correlation was good between the 2 modalities (κ = 0.61). The interobserver correlation between the 2 MDCT readers ranged from good (r = 0.72 for LV end-diastolic volume) to excellent (r = 0.84 for septal wall thickness). In conclusion, MDCT provides comparable results to TTE for LV structure and functional assessment among patients with HF.

    Original languageEnglish (US)
    Pages (from-to)247-249
    Number of pages3
    JournalAmerican Journal of Cardiology
    Volume99
    Issue number2
    DOIs
    StatePublished - Jan 15 2007

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine

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