Antimouse antibody is produced from 40 to 68% of the time after administration of Orthoclone OKT3. In patients treated with OKT3, however, if the concomitant immunosuppression is not decreased, the incidence of the antibody production is reduced to 40%. Similarly, 33% of patients developed antihorse antibody after the initial antithymocyte globulin (ATG) administration. Most of the time, the antibody production is low-titered for both OKT3 and ATG.
|Original language||English (US)|
|Number of pages||4|
|Issue number||SUPPL. 1|
|State||Published - Sep 10 1987|
ASJC Scopus subject areas
- Physiology (medical)