Comparison of a novel adaptive lens with deformable mirrors and its application in high-resolution in-vivo OCT imaging

Luca Rizzotto, Stefano Bonora, Yifan Jian, Pengfei Zhang, Azhar Zam, Edward N. Pugh, F. Mammano, Robert J. Zawadzki, Marinko V. Sarunic

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present a novel adaptive lens that can correct high order aberrations, and which has the potential to increase the diffusion of adaptive optics to many new applications by simplifying the integration of a wavefront corrector inside existing systems. The adaptive lens design that we present can correct for Zernike wavefront aberrations up to the 4th order. The adaptive lens performance are compared with the one of a membrane and bimorph deformable mirrors used together in a wide field microscope setup, using a Shack-Hartmann wavefront sensor for closed loop control. The adaptive lens was also integrated with Fourier Domain Optical Coherence Tomography for in-vivo imaging of mouse retinal structures using an image based wavefront sensorless control.

Original languageEnglish (US)
Title of host publicationAdaptive Optics and Wavefront Control for Biological Systems
EditorsJoel Kubby, Sylvain Gigan, Thomas G. Bifano
PublisherSPIE
ISBN (Electronic)9781628414257
DOIs
StatePublished - Jan 1 2015
Externally publishedYes
EventAdaptive Optics and Wavefront Control for Biological Systems - San Francisco, United States
Duration: Feb 7 2015Feb 9 2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9335
ISSN (Print)1605-7422

Conference

ConferenceAdaptive Optics and Wavefront Control for Biological Systems
CountryUnited States
CitySan Francisco
Period2/7/152/9/15

Fingerprint

deformable mirrors
Wavefronts
Lenses
lenses
Imaging techniques
aberration
high resolution
Aberrations
lens design
adaptive optics
mice
Adaptive optics
Optical tomography
Optical Coherence Tomography
tomography
microscopes
membranes
Microscopes
sensors
Membranes

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

Rizzotto, L., Bonora, S., Jian, Y., Zhang, P., Zam, A., Pugh, E. N., ... Sarunic, M. V. (2015). Comparison of a novel adaptive lens with deformable mirrors and its application in high-resolution in-vivo OCT imaging. In J. Kubby, S. Gigan, & T. G. Bifano (Eds.), Adaptive Optics and Wavefront Control for Biological Systems [933514] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9335). SPIE. https://doi.org/10.1117/12.2180145

Comparison of a novel adaptive lens with deformable mirrors and its application in high-resolution in-vivo OCT imaging. / Rizzotto, Luca; Bonora, Stefano; Jian, Yifan; Zhang, Pengfei; Zam, Azhar; Pugh, Edward N.; Mammano, F.; Zawadzki, Robert J.; Sarunic, Marinko V.

Adaptive Optics and Wavefront Control for Biological Systems. ed. / Joel Kubby; Sylvain Gigan; Thomas G. Bifano. SPIE, 2015. 933514 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9335).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Rizzotto, L, Bonora, S, Jian, Y, Zhang, P, Zam, A, Pugh, EN, Mammano, F, Zawadzki, RJ & Sarunic, MV 2015, Comparison of a novel adaptive lens with deformable mirrors and its application in high-resolution in-vivo OCT imaging. in J Kubby, S Gigan & TG Bifano (eds), Adaptive Optics and Wavefront Control for Biological Systems., 933514, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 9335, SPIE, Adaptive Optics and Wavefront Control for Biological Systems, San Francisco, United States, 2/7/15. https://doi.org/10.1117/12.2180145
Rizzotto L, Bonora S, Jian Y, Zhang P, Zam A, Pugh EN et al. Comparison of a novel adaptive lens with deformable mirrors and its application in high-resolution in-vivo OCT imaging. In Kubby J, Gigan S, Bifano TG, editors, Adaptive Optics and Wavefront Control for Biological Systems. SPIE. 2015. 933514. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2180145
Rizzotto, Luca ; Bonora, Stefano ; Jian, Yifan ; Zhang, Pengfei ; Zam, Azhar ; Pugh, Edward N. ; Mammano, F. ; Zawadzki, Robert J. ; Sarunic, Marinko V. / Comparison of a novel adaptive lens with deformable mirrors and its application in high-resolution in-vivo OCT imaging. Adaptive Optics and Wavefront Control for Biological Systems. editor / Joel Kubby ; Sylvain Gigan ; Thomas G. Bifano. SPIE, 2015. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
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