Common bile duct obstruction related to intestinal polyposis in a child with Peutz-Jeghers syndrome

Andrew T. Gentile, Stephen W. Bickler, Marvin W. Harrison, John R. Campbell

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Peutz-Jeghers syndrome is characterized by hamartomatous polyposis of the small and large bowel and mucocutaneous pigmentation. The authors describe a 9-year-old girl with small bowel obstruction related to duodenal intussusception caused by polyposis in the fourth portion of the duodenum. Operative reduction of the intussusception and excision of the polyps were performed, at which time the pancreas appeared to have mild pancreatitis. A liver biopsy specimen showed mild portal fibrosis and ductal proliferation. The patient did well postoperatively, but later presented with symptoms consistent with biliary obstruction. Percutaneous transhepatic cholangiography showed pancreatic and biliary duct dilatation as well as obstruction of the common bile duct, which extended into the left upper quadrant. Exploration showed ampullary obstruction several centimeters proximal to the line of resection. Sphincteroplasty was performed. The postoperative course was uncomplicated. The authors conclude that Peutz-Jeghers syndrome with polyps in the duodenum can markedly distort duodenal and ductal anatomy and can lead to ampullary obstruction.

Original languageEnglish (US)
Pages (from-to)1584-1587
Number of pages4
JournalJournal of Pediatric Surgery
Volume29
Issue number12
DOIs
StatePublished - 1994

Fingerprint

Intestinal Polyposis
Peutz-Jeghers Syndrome
Intussusception
Cholestasis
Common Bile Duct
Polyps
Duodenum
Cholangiography
Pancreatic Ducts
Pigmentation
Pancreatitis
Dilatation
Pancreas
Anatomy
Fibrosis
Biopsy
Liver

Keywords

  • biliary obstruction
  • hamartomatous polyposis
  • intussusception
  • Peutz-Jeghers

ASJC Scopus subject areas

  • Surgery

Cite this

Common bile duct obstruction related to intestinal polyposis in a child with Peutz-Jeghers syndrome. / Gentile, Andrew T.; Bickler, Stephen W.; Harrison, Marvin W.; Campbell, John R.

In: Journal of Pediatric Surgery, Vol. 29, No. 12, 1994, p. 1584-1587.

Research output: Contribution to journalArticle

Gentile, Andrew T. ; Bickler, Stephen W. ; Harrison, Marvin W. ; Campbell, John R. / Common bile duct obstruction related to intestinal polyposis in a child with Peutz-Jeghers syndrome. In: Journal of Pediatric Surgery. 1994 ; Vol. 29, No. 12. pp. 1584-1587.
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