Combining Comparative Proteomics and Molecular Genetics Uncovers Regulators of Synaptic and Axonal Stability and Degeneration In Vivo

Agriculture & Biology

• synapse 91%
• molecular genetics 79%
• proteomics 71%
• synaptic transmission 56%
• neurons 33%
• brain 28%
• mutation 27%
• proteins 27%
• calcium-binding proteins 25%
• neurites 25%
• neurodegenerative diseases 25%
• modifiers (genes) 25%
• molecular chaperones 24%
• mutants 23%
• mice 23%
• axons 20%
• proteome 19%
• pathogenesis 18%
• genetic analysis 18%
• animal models 17%
• Drosophila 17%
• therapeutics 15%
• genetic markers 15%

Medicine & Life Sciences

• Proteomics 74%
• Synapses 74%
• Molecular Biology 65%
• Synaptic Transmission 37%
• Spinocerebellar Ataxias 27%
• Synaptic Potentials 25%
• Calcium-Binding Proteins 25%
• Neurons 24%
• Molecular Chaperones 24%
• Mutation 22%
• Neurites 22%
• Huntington Disease 22%
• Proteins 22%
• Mutant Proteins 21%
• Proteome 21%
• Wounds and Injuries 19%
• Brain Injuries 19%
• Computer Simulation 19%
• Drosophila 18%
• Cluster Analysis 18%
• Axons 17%
• Neurodegenerative Diseases 17%
• Brain 9%
• Therapeutics 3%

Earth & Environmental Sciences

• proteomics 100%
• protein 58%
• mutant 34%
• mutation 32%
• top-down approach 21%
• genetic analysis 21%
• targeting 15%
• marker 13%
• perturbation 12%
• calcium 12%
• loss 8%