Coisogenic Strain

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A coisogenic pair of strains differs only at a single genetic locus. A coisogenic strain can occur as the result of a random mutation, or can be created using genetic engineering, chemical mutagenesis, or irradiation. Comparison of a coisogenic pair of strains is a powerful method for detecting the effects of a single gene.

Original languageEnglish (US)
Title of host publicationBrenner's Encyclopedia of Genetics
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Pages84
Number of pages1
ISBN (Electronic)9780080961569
ISBN (Print)9780123749840
DOIs
Publication statusPublished - Feb 27 2013

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Keywords

  • Allele
  • Chemical mutagenesis
  • Congenic strain
  • Embryonic cells
  • Genetic engineering
  • Inbred strain
  • Irradiation
  • Random mutagenesis
  • Single-gene mutant
  • Spontaneous mutation

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Phillips, T. (2013). Coisogenic Strain. In Brenner's Encyclopedia of Genetics: Second Edition (pp. 84). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-374984-0.00287-4