Cobalt plaque versus enucleation for uveal melanoma: Comparison of survival rates

Kimberley S. Adams, David H. Abramson, Robert M. Ellsworth, Barrett G. Haik, Michael Bedford, Samuel Packer, Johanna Seddon, Daniel Albert, Lela Polivogianis

Research output: Contribution to journalArticlepeer-review

66 Scopus citations

Abstract

Two hundred and twenty-three patients treated by cobalt plaque for uveal melanoma were compared with 416 patients treated by enucleation for uveal melanoma in terms of patient survival. The median follow-up time for the patients treated by cobalt plaque was 4·3 years. Kaplan-Meier survival curves were calculated up to five years following treatment based on time to tumour-related deaths. Cox's proportional hazards multivariate analysis was performed to determine which variables were related to melanoma-related deaths while controlling for age, size, and location of the tumours. Statistically significant predictive factors were location of tumour and largest tumour dimension. There was not a statistically significant difference in survival between patients treated by cobalt plaque and those treated by enucleation.

Original languageEnglish (US)
Pages (from-to)494-497
Number of pages4
JournalBritish Journal of Ophthalmology
Volume72
Issue number7
DOIs
StatePublished - 1988

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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