Cobalt plaque versus enucleation for uveal melanoma: Comparison of survival rates

Kimberley S. Adams, David H. Abramson, Robert M. Ellsworth, Barrett G. Haik, Michael Bedford, Samuel Packer, Johanna Seddon, Daniel Albert, Lela Polivogianis

Research output: Contribution to journalArticle

66 Scopus citations

Abstract

Two hundred and twenty-three patients treated by cobalt plaque for uveal melanoma were compared with 416 patients treated by enucleation for uveal melanoma in terms of patient survival. The median follow-up time for the patients treated by cobalt plaque was 4·3 years. Kaplan-Meier survival curves were calculated up to five years following treatment based on time to tumour-related deaths. Cox's proportional hazards multivariate analysis was performed to determine which variables were related to melanoma-related deaths while controlling for age, size, and location of the tumours. Statistically significant predictive factors were location of tumour and largest tumour dimension. There was not a statistically significant difference in survival between patients treated by cobalt plaque and those treated by enucleation.

Original languageEnglish (US)
Pages (from-to)494-497
Number of pages4
JournalBritish Journal of Ophthalmology
Volume72
Issue number7
DOIs
StatePublished - 1988

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Fingerprint Dive into the research topics of 'Cobalt plaque versus enucleation for uveal melanoma: Comparison of survival rates'. Together they form a unique fingerprint.

  • Cite this

    Adams, K. S., Abramson, D. H., Ellsworth, R. M., Haik, B. G., Bedford, M., Packer, S., Seddon, J., Albert, D., & Polivogianis, L. (1988). Cobalt plaque versus enucleation for uveal melanoma: Comparison of survival rates. British Journal of Ophthalmology, 72(7), 494-497. https://doi.org/10.1136/bjo.72.7.494