Cobalt plaque versus enucleation for uveal melanoma: Comparison of survival rates

Kimberley S. Adams, David H. Abramson, Robert M. Ellsworth, Barrett G. Haik, Michael Bedford, Samuel Packer, Johanna Seddon, Daniel Albert, Lela Polivogianis

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Two hundred and twenty-three patients treated by cobalt plaque for uveal melanoma were compared with 416 patients treated by enucleation for uveal melanoma in terms of patient survival. The median follow-up time for the patients treated by cobalt plaque was 4·3 years. Kaplan-Meier survival curves were calculated up to five years following treatment based on time to tumour-related deaths. Cox's proportional hazards multivariate analysis was performed to determine which variables were related to melanoma-related deaths while controlling for age, size, and location of the tumours. Statistically significant predictive factors were location of tumour and largest tumour dimension. There was not a statistically significant difference in survival between patients treated by cobalt plaque and those treated by enucleation.

Original languageEnglish (US)
Pages (from-to)494-497
Number of pages4
JournalBritish Journal of Ophthalmology
Volume72
Issue number7
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

Fingerprint

Cobalt
Survival Rate
Neoplasms
Survival
Kaplan-Meier Estimate
Melanoma
Multivariate Analysis
Uveal melanoma
Therapeutics

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Emergency Medicine
  • Ophthalmology

Cite this

Adams, K. S., Abramson, D. H., Ellsworth, R. M., Haik, B. G., Bedford, M., Packer, S., ... Polivogianis, L. (1988). Cobalt plaque versus enucleation for uveal melanoma: Comparison of survival rates. British Journal of Ophthalmology, 72(7), 494-497. https://doi.org/10.1136/bjo.72.7.494

Cobalt plaque versus enucleation for uveal melanoma : Comparison of survival rates. / Adams, Kimberley S.; Abramson, David H.; Ellsworth, Robert M.; Haik, Barrett G.; Bedford, Michael; Packer, Samuel; Seddon, Johanna; Albert, Daniel; Polivogianis, Lela.

In: British Journal of Ophthalmology, Vol. 72, No. 7, 01.01.1988, p. 494-497.

Research output: Contribution to journalArticle

Adams, KS, Abramson, DH, Ellsworth, RM, Haik, BG, Bedford, M, Packer, S, Seddon, J, Albert, D & Polivogianis, L 1988, 'Cobalt plaque versus enucleation for uveal melanoma: Comparison of survival rates', British Journal of Ophthalmology, vol. 72, no. 7, pp. 494-497. https://doi.org/10.1136/bjo.72.7.494
Adams KS, Abramson DH, Ellsworth RM, Haik BG, Bedford M, Packer S et al. Cobalt plaque versus enucleation for uveal melanoma: Comparison of survival rates. British Journal of Ophthalmology. 1988 Jan 1;72(7):494-497. https://doi.org/10.1136/bjo.72.7.494
Adams, Kimberley S. ; Abramson, David H. ; Ellsworth, Robert M. ; Haik, Barrett G. ; Bedford, Michael ; Packer, Samuel ; Seddon, Johanna ; Albert, Daniel ; Polivogianis, Lela. / Cobalt plaque versus enucleation for uveal melanoma : Comparison of survival rates. In: British Journal of Ophthalmology. 1988 ; Vol. 72, No. 7. pp. 494-497.
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