Coaggregation Interactions Between Oral and Endodontic Enterococcus faecalis and Bacterial Species Isolated From Persistent Apical Periodontitis

Erika M. Johnson, Susan E. Flannagan, Christine Sedgley

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Interactions between Enterococcus faecalis and other species found in root canal infections might be important for the development and persistence of periapical disease. The aim of this study was to investigate the coaggregation interactions between E. faecalis clinical isolates and species previously shown to survive and induce apical periodontitis in monkeys: Peptostreptococcus anaerobius, Prevotella oralis, Fusobacterium nucleatum, and Streptococcus anginosus. Intergeneric coaggregation assays were conducted in duplicate with observations scored immediately at 0 h, 1 h and 24 h after mixing of combinations of strains. All E. faecalis strains (n = 53) coaggregated with F. nucleatum; E. faecalis did not coaggregate with P. anaerobius or S. anginosus. One strain, E. faecalis E1, coaggregated with P. oralis, with aggregates visible at 1 h. Coaggregation interactions between E. faecalis and F. nucleatum observed in this study suggest a potential role for this combination in endodontic infections.

Original languageEnglish (US)
Pages (from-to)946-950
Number of pages5
JournalJournal of Endodontics
Volume32
Issue number10
DOIs
StatePublished - Oct 2006
Externally publishedYes

Fingerprint

Periapical Periodontitis
Enterococcus faecalis
Endodontics
Fusobacterium nucleatum
Streptococcus anginosus
Periapical Diseases
Prevotella
Peptostreptococcus
Dental Pulp Cavity
Infection
Haplorhini

Keywords

  • Apical periodontitis
  • bacteria
  • coaggregation
  • endodontic
  • Enterococcus faecalis

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Coaggregation Interactions Between Oral and Endodontic Enterococcus faecalis and Bacterial Species Isolated From Persistent Apical Periodontitis. / Johnson, Erika M.; Flannagan, Susan E.; Sedgley, Christine.

In: Journal of Endodontics, Vol. 32, No. 10, 10.2006, p. 946-950.

Research output: Contribution to journalArticle

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