Coaggregation Interactions Between Oral and Endodontic Enterococcus faecalis and Bacterial Species Isolated From Persistent Apical Periodontitis

Erika M. Johnson, Susan E. Flannagan, Christine M. Sedgley

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Interactions between Enterococcus faecalis and other species found in root canal infections might be important for the development and persistence of periapical disease. The aim of this study was to investigate the coaggregation interactions between E. faecalis clinical isolates and species previously shown to survive and induce apical periodontitis in monkeys: Peptostreptococcus anaerobius, Prevotella oralis, Fusobacterium nucleatum, and Streptococcus anginosus. Intergeneric coaggregation assays were conducted in duplicate with observations scored immediately at 0 h, 1 h and 24 h after mixing of combinations of strains. All E. faecalis strains (n = 53) coaggregated with F. nucleatum; E. faecalis did not coaggregate with P. anaerobius or S. anginosus. One strain, E. faecalis E1, coaggregated with P. oralis, with aggregates visible at 1 h. Coaggregation interactions between E. faecalis and F. nucleatum observed in this study suggest a potential role for this combination in endodontic infections.

Original languageEnglish (US)
Pages (from-to)946-950
Number of pages5
JournalJournal of endodontics
Volume32
Issue number10
DOIs
StatePublished - Oct 1 2006

Keywords

  • Apical periodontitis
  • Enterococcus faecalis
  • bacteria
  • coaggregation
  • endodontic

ASJC Scopus subject areas

  • Dentistry(all)

Fingerprint Dive into the research topics of 'Coaggregation Interactions Between Oral and Endodontic Enterococcus faecalis and Bacterial Species Isolated From Persistent Apical Periodontitis'. Together they form a unique fingerprint.

Cite this