Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases

James A. Hejna, Hiroshi Saito, Louise S. Merkens, Thomas V. Tittle, Petra M. Jakobs, Michael A. Whitney, Markus Grompe, Andrew S. Friedberg, Robb E. Moses

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

We have cloned a novel human cDNA, INPPL1 (GenBank Accession No. L36818), which maps to 11q23. The corresponding mRNA is 4657 nt in length and is widely expressed in both fetal and adult tissues. An open reading frame of 3441 nt encodes a putative polypeptide that shares several domains with inositol triphosphate phosphatases. Several polymorphisms have been mapped to the 3′-untranslated region, yet the putative coding region showed no polymorphisms in nine independent cDNA samples.

Original languageEnglish (US)
Pages (from-to)285-287
Number of pages3
JournalGenomics
Volume29
Issue number1
DOIs
StatePublished - Sep 1 1995

ASJC Scopus subject areas

  • Genetics

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    Hejna, J. A., Saito, H., Merkens, L. S., Tittle, T. V., Jakobs, P. M., Whitney, M. A., Grompe, M., Friedberg, A. S., & Moses, R. E. (1995). Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases. Genomics, 29(1), 285-287. https://doi.org/10.1006/geno.1995.1247