Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases

James A. Hejna; Hiroshi Saito; Louise S. Merkens; Thomas V. Tittle; Petra M. Jakobs; Michael A. Whitney; Markus Grompe; Andrew S. Friedberg; Robb E. Moses

doi:10.1006/geno.1995.1247

Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases

James A. Hejna, Hiroshi Saito, Louise S. Merkens, Thomas V. Tittle, Petra M. Jakobs, Michael A. Whitney, Markus Grompe, Andrew S. Friedberg, Robb E. Moses

Research output: Contribution to journal › Article › peer-review

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Abstract

We have cloned a novel human cDNA, INPPL1 (GenBank Accession No. L36818), which maps to 11q23. The corresponding mRNA is 4657 nt in length and is widely expressed in both fetal and adult tissues. An open reading frame of 3441 nt encodes a putative polypeptide that shares several domains with inositol triphosphate phosphatases. Several polymorphisms have been mapped to the 3′-untranslated region, yet the putative coding region showed no polymorphisms in nine independent cDNA samples.

Original language	English (US)
Pages (from-to)	285-287
Number of pages	3
Journal	Genomics
Volume	29
Issue number	1
DOIs	https://doi.org/10.1006/geno.1995.1247
State	Published - Sep 1 1995

ASJC Scopus subject areas

Genetics

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abstract = "We have cloned a novel human cDNA, INPPL1 (GenBank Accession No. L36818), which maps to 11q23. The corresponding mRNA is 4657 nt in length and is widely expressed in both fetal and adult tissues. An open reading frame of 3441 nt encodes a putative polypeptide that shares several domains with inositol triphosphate phosphatases. Several polymorphisms have been mapped to the 3′-untranslated region, yet the putative coding region showed no polymorphisms in nine independent cDNA samples.",

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T1 - Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases

AU - Hejna, James A.

AU - Saito, Hiroshi

AU - Merkens, Louise S.

AU - Tittle, Thomas V.

AU - Jakobs, Petra M.

AU - Whitney, Michael A.

AU - Grompe, Markus

AU - Friedberg, Andrew S.

AU - Moses, Robb E.

PY - 1995/9/1

Y1 - 1995/9/1

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AB - We have cloned a novel human cDNA, INPPL1 (GenBank Accession No. L36818), which maps to 11q23. The corresponding mRNA is 4657 nt in length and is widely expressed in both fetal and adult tissues. An open reading frame of 3441 nt encodes a putative polypeptide that shares several domains with inositol triphosphate phosphatases. Several polymorphisms have been mapped to the 3′-untranslated region, yet the putative coding region showed no polymorphisms in nine independent cDNA samples.

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Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases

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