Clonidine reduces plasma melatonin levels

A. J. Lewy, L. J. Siever, T. W. Uhde, S. P. Markey

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


Clonidine, an α‐adrenoceptor agonist, reduces human plasma melatonin levels when administered intravenously at 2–3 (μg kg−1 to sleeping volunteers. Measurement of plasma melatonin levels after administration of clonidine could be the basis for a clinical in‐vivo test of α‐adrenoceptors.

Original languageEnglish (US)
Pages (from-to)555-556
Number of pages2
JournalJournal of Pharmacy and Pharmacology
Issue number7
StatePublished - Jul 1986

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science


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