TY - JOUR
T1 - Clinical impact of neonatal hypoglycemia screening in the well-baby care
AU - Mukhopadhyay, Sagori
AU - Wade, Kelly C.
AU - Dhudasia, Miren B.
AU - Skerritt, Lauren
AU - Chou, Joseph H.
AU - Dukhovny, Dmitry
AU - Puopolo, Karen M.
N1 - Funding Information:
Funding This study was partly supported by Eunice Kennedy Shriver National Institute of Child Health and Human Development Grant (Number—1K23HD088753-01A1).
Publisher Copyright:
© 2020, The Author(s), under exclusive licence to Springer Nature America, Inc.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Objectives: To determine the proportion of well-appearing newborns screened for hypoglycemia, yield of specific screening criteria, and impact of screening on breastfeeding. Study design: The retrospective study of well-appearing at-risk infants born ≥36 weeks’ gestation with blood glucose (BG) measurements obtained ≤72 h of age. Results: Of 10,533 eligible well newborns, 48.7% were screened for hypoglycemia. Among tested infants, BG < 50 mg/dL occurred in 43% and 4.6% required intensive care for hypoglycemia. BG < 50 mg/dL was associated with lower rates of exclusive breastfeeding (22% vs 65%, p < 0.001). Infants screened due to late-preterm birth were most frequently identified as hypoglycemic. The fewest abnormal values occurred among appropriate weight, late-term infants of nondiabetic mothers. Conclusion: Hypoglycemia risk criteria result in screening a large proportion of otherwise well newborns and negatively impact rates of exclusive breastfeeding. The risks and benefits of hypoglycemia screening recommendations should be urgently addressed.
AB - Objectives: To determine the proportion of well-appearing newborns screened for hypoglycemia, yield of specific screening criteria, and impact of screening on breastfeeding. Study design: The retrospective study of well-appearing at-risk infants born ≥36 weeks’ gestation with blood glucose (BG) measurements obtained ≤72 h of age. Results: Of 10,533 eligible well newborns, 48.7% were screened for hypoglycemia. Among tested infants, BG < 50 mg/dL occurred in 43% and 4.6% required intensive care for hypoglycemia. BG < 50 mg/dL was associated with lower rates of exclusive breastfeeding (22% vs 65%, p < 0.001). Infants screened due to late-preterm birth were most frequently identified as hypoglycemic. The fewest abnormal values occurred among appropriate weight, late-term infants of nondiabetic mothers. Conclusion: Hypoglycemia risk criteria result in screening a large proportion of otherwise well newborns and negatively impact rates of exclusive breastfeeding. The risks and benefits of hypoglycemia screening recommendations should be urgently addressed.
UR - http://www.scopus.com/inward/record.url?scp=85081682775&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85081682775&partnerID=8YFLogxK
U2 - 10.1038/s41372-020-0641-1
DO - 10.1038/s41372-020-0641-1
M3 - Article
C2 - 32152490
AN - SCOPUS:85081682775
SN - 0743-8346
VL - 40
SP - 1331
EP - 1338
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 9
ER -