Clinical impact of neonatal hypoglycemia screening in the well-baby care

Sagori Mukhopadhyay, Kelly C. Wade, Miren B. Dhudasia, Lauren Skerritt, Joseph H. Chou, Dmitry Dukhovny, Karen M. Puopolo

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Objectives: To determine the proportion of well-appearing newborns screened for hypoglycemia, yield of specific screening criteria, and impact of screening on breastfeeding. Study design: The retrospective study of well-appearing at-risk infants born ≥36 weeks’ gestation with blood glucose (BG) measurements obtained ≤72 h of age. Results: Of 10,533 eligible well newborns, 48.7% were screened for hypoglycemia. Among tested infants, BG < 50 mg/dL occurred in 43% and 4.6% required intensive care for hypoglycemia. BG < 50 mg/dL was associated with lower rates of exclusive breastfeeding (22% vs 65%, p < 0.001). Infants screened due to late-preterm birth were most frequently identified as hypoglycemic. The fewest abnormal values occurred among appropriate weight, late-term infants of nondiabetic mothers. Conclusion: Hypoglycemia risk criteria result in screening a large proportion of otherwise well newborns and negatively impact rates of exclusive breastfeeding. The risks and benefits of hypoglycemia screening recommendations should be urgently addressed.

Original languageEnglish (US)
Pages (from-to)1331-1338
Number of pages8
JournalJournal of Perinatology
Issue number9
StatePublished - Sep 1 2020

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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