Clinical Dilemmas in Anticoagulation: Extremes of Weight, Renal Disease, Recent Bleeding, and Surgery

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Clinical trials of antithrombotic agents enrolled thousands of patients and form the basis of current recommendations for therapy. However, many patients with thrombosis were not adequately represented in clinical trials. These would include patients at extremes of weight, those with renal disease, those with recent bleeding, and those who need surgery. This chapter reviews many challenging clinical situations such as anticoagulation in those with renal disease and restarting anticoagulation after bleeding. Recommendations are made based on the limited data available.

Original languageEnglish (US)
Title of host publicationHemostasis and Thrombosis
Subtitle of host publicationFourth Edition
PublisherSpringer International Publishing
Pages179-185
Number of pages7
ISBN (Electronic)9783030193300
ISBN (Print)9783030193294
DOIs
StatePublished - Jan 1 2019

Keywords

  • Antithrombotic therapy
  • Direct oral anticoagulants
  • Pregnancy
  • Renal disease

ASJC Scopus subject areas

  • General Medicine

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