Abstract
Clinical trials of antithrombotic agents enrolled thousands of patients and form the basis of current recommendations for therapy. However, many patients with thrombosis were not adequately represented in clinical trials. These would include patients at extremes of weight, those with renal disease, those with recent bleeding, and those who need surgery. This chapter reviews many challenging clinical situations such as anticoagulation in those with renal disease and restarting anticoagulation after bleeding. Recommendations are made based on the limited data available.
Original language | English (US) |
---|---|
Title of host publication | Hemostasis and Thrombosis |
Subtitle of host publication | Fourth Edition |
Publisher | Springer International Publishing |
Pages | 179-185 |
Number of pages | 7 |
ISBN (Electronic) | 9783030193300 |
ISBN (Print) | 9783030193294 |
DOIs | |
State | Published - Jan 1 2019 |
Keywords
- Antithrombotic therapy
- Direct oral anticoagulants
- Pregnancy
- Renal disease
ASJC Scopus subject areas
- General Medicine