Clinical challenge – scratching the surface of the sheath

Jiwei Sheng, Christopher Dermarkarian, Rod Foroozan, Julie Falardeau

Research output: Contribution to journalEditorialpeer-review


A 63-year-old white man with hypertension, hyperlipidemia, adrenal insufficiency, and history of metastatic spindle cell melanoma previously treated with ipilimumab, presented with unilateral papillitis in the left eye. The disc edema evolved to neuroretinitis with additional MRI findings of perineuritis. Broad laboratory evaluation confirmed active B. henselae infection, and he confirmed exposure to a newly adopted kitten. His vision improved following a course of antibiotics and oral steroids with resolution of clinical findings. To the best of our knowledge, this is the first reported case of cat-scratch neuroretinitis with MRI findings of optic nerve and optic nerve sheath enhancement.

Original languageEnglish (US)
JournalSurvey of Ophthalmology
StateAccepted/In press - 2021
Externally publishedYes


  • Bartonella antibodies
  • Bartonella henselae
  • Bartonella PCR
  • Ipilimumab
  • Melanoma
  • MRI
  • Neuroretinitis
  • Papillitis
  • Perineuritis

ASJC Scopus subject areas

  • Ophthalmology


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