CLINICAL, BACTERIOLOGICAL, AND IMMUNOLOGICAL CHARACTERISATION OF AMPICILLIN-RESISTANT HÆMOPHILUS INFLUENZÆ TYPE B

M. S. Schiffer; R. Schneerson; J. Maclowry; J. B. Robbins; J. W. Mcreynolds; W. J. Thomas; D. W. Bailey; E. J. Clarke; E. J. Mueller; J. Escamilla

doi:10.1016/S0140-6736(74)91416-0

CLINICAL, BACTERIOLOGICAL, AND IMMUNOLOGICAL CHARACTERISATION OF AMPICILLIN-RESISTANT HÆMOPHILUS INFLUENZÆ TYPE B

M. S. Schiffer, R. Schneerson, J. Maclowry, J. B. Robbins, J. W. Mcreynolds, W. J. Thomas, D. W. Bailey, E. J. Clarke, E. J. Mueller, J. Escamilla

Pathology

Research output: Contribution to journal › Article

46 Scopus citations

Abstract

Ampicillin-resistant Hæmophilus influenzæ type b (H.I.T.B.) was isolated from the cerebrospinal fluid of 1 of 3 children with H.I.T.B. meningitis, attending the same day-care centre. 81 children and 13 adults, from the same area as the 3 cases, were examined for nasopharyngeal carriage of H.I.T.B. Six ampicillin-resistant and four ampicillin-sensitive strains were recovered from the children. When 46 of these children were re-examined and had blood drawn one month later, 11 carriers of H.I.T.B. were found. High levels of H.I.T.B. antibody were associated with persistent carriage of either the ampicillin resistant or sensitive strains. All isolates from children at the day-care centre were ampicillin resistant during both surveys.

Original language	English (US)
Pages (from-to)	257-259
Number of pages	3
Journal	The Lancet
Volume	304
Issue number	7875
DOIs	https://doi.org/10.1016/S0140-6736(74)91416-0
State	Published - Aug 3 1974

ASJC Scopus subject areas

Medicine(all)

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CLINICAL, BACTERIOLOGICAL, AND IMMUNOLOGICAL CHARACTERISATION OF AMPICILLIN-RESISTANT HÆMOPHILUS INFLUENZÆ TYPE B. / Schiffer, M. S.; Schneerson, R.; Maclowry, J.; Robbins, J. B.; Mcreynolds, J. W.; Thomas, W. J.; Bailey, D. W.; Clarke, E. J.; Mueller, E. J.; Escamilla, J.

In: The Lancet, Vol. 304, No. 7875, 03.08.1974, p. 257-259.

Research output: Contribution to journal › Article

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title = "CLINICAL, BACTERIOLOGICAL, AND IMMUNOLOGICAL CHARACTERISATION OF AMPICILLIN-RESISTANT H{\AE}MOPHILUS INFLUENZ{\AE} TYPE B",

abstract = "Ampicillin-resistant H{\ae}mophilus influenz{\ae} type b (H.I.T.B.) was isolated from the cerebrospinal fluid of 1 of 3 children with H.I.T.B. meningitis, attending the same day-care centre. 81 children and 13 adults, from the same area as the 3 cases, were examined for nasopharyngeal carriage of H.I.T.B. Six ampicillin-resistant and four ampicillin-sensitive strains were recovered from the children. When 46 of these children were re-examined and had blood drawn one month later, 11 carriers of H.I.T.B. were found. High levels of H.I.T.B. antibody were associated with persistent carriage of either the ampicillin resistant or sensitive strains. All isolates from children at the day-care centre were ampicillin resistant during both surveys.",

author = "Schiffer, {M. S.} and R. Schneerson and J. Maclowry and Robbins, {J. B.} and Mcreynolds, {J. W.} and Thomas, {W. J.} and Bailey, {D. W.} and Clarke, {E. J.} and Mueller, {E. J.} and J. Escamilla",

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doi = "10.1016/S0140-6736(74)91416-0",

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AU - Schneerson, R.

AU - Maclowry, J.

AU - Robbins, J. B.

AU - Mcreynolds, J. W.

AU - Thomas, W. J.

AU - Bailey, D. W.

AU - Clarke, E. J.

AU - Mueller, E. J.

AU - Escamilla, J.

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