Clinical and histopathologic observations regarding cell death and tumor necrosis in retinoblastoma

D. M. Albert, D. N. Sang, J. L. Craft

Research output: Contribution to journalArticle

5 Scopus citations


The frequent occurrence of spontaneous regression of retinoblastoma is a striking characteristic of this tumor. The induction of regression of tumors by various therapeutic means has increasingly become the goal in the management of retinoblastoma patients as a desirable alternative to enucleation. The basic mechanisms involved in spontaneous or induced regression of retinoblastoma have important implications in regard to the field of cancer biology.

Original languageEnglish (US)
Pages (from-to)358-374
Number of pages17
JournalJapanese Journal of Ophthalmology
Issue number3
StatePublished - Jan 1 1978


ASJC Scopus subject areas

  • Ophthalmology

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