Circadian misalignment in major depressive disorder

Jonathan Emens, Alfred Lewy, John (Mark) Kinzie, Diana Arntz, Jennifer Rough

Research output: Contribution to journalArticle

138 Citations (Scopus)

Abstract

It has been hypothesized that the circadian pacemaker plays a role in major depressive disorder (MDD). We sought to determine if misalignment between the timing of sleep and the pacemaker correlated with symptom severity in MDD. Depression severity correlated with circadian misalignment: the more delayed, the more severe the symptoms.

Original languageEnglish (US)
Pages (from-to)259-261
Number of pages3
JournalPsychiatry Research
Volume168
Issue number3
DOIs
StatePublished - Aug 15 2009

Fingerprint

Major Depressive Disorder
Sleep
Depression

Keywords

  • Circadian rhythms
  • Depression
  • Dim light melatonin onset (DLMO)
  • Melatonin
  • Phase angle difference (PAD)
  • Sleep

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Circadian misalignment in major depressive disorder. / Emens, Jonathan; Lewy, Alfred; Kinzie, John (Mark); Arntz, Diana; Rough, Jennifer.

In: Psychiatry Research, Vol. 168, No. 3, 15.08.2009, p. 259-261.

Research output: Contribution to journalArticle

Emens, Jonathan ; Lewy, Alfred ; Kinzie, John (Mark) ; Arntz, Diana ; Rough, Jennifer. / Circadian misalignment in major depressive disorder. In: Psychiatry Research. 2009 ; Vol. 168, No. 3. pp. 259-261.
@article{b735e9c47e2e4195b3718c0e058f5b95,
title = "Circadian misalignment in major depressive disorder",
abstract = "It has been hypothesized that the circadian pacemaker plays a role in major depressive disorder (MDD). We sought to determine if misalignment between the timing of sleep and the pacemaker correlated with symptom severity in MDD. Depression severity correlated with circadian misalignment: the more delayed, the more severe the symptoms.",
keywords = "Circadian rhythms, Depression, Dim light melatonin onset (DLMO), Melatonin, Phase angle difference (PAD), Sleep",
author = "Jonathan Emens and Alfred Lewy and Kinzie, {John (Mark)} and Diana Arntz and Jennifer Rough",
year = "2009",
month = "8",
day = "15",
doi = "10.1016/j.psychres.2009.04.009",
language = "English (US)",
volume = "168",
pages = "259--261",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

TY - JOUR

T1 - Circadian misalignment in major depressive disorder

AU - Emens, Jonathan

AU - Lewy, Alfred

AU - Kinzie, John (Mark)

AU - Arntz, Diana

AU - Rough, Jennifer

PY - 2009/8/15

Y1 - 2009/8/15

N2 - It has been hypothesized that the circadian pacemaker plays a role in major depressive disorder (MDD). We sought to determine if misalignment between the timing of sleep and the pacemaker correlated with symptom severity in MDD. Depression severity correlated with circadian misalignment: the more delayed, the more severe the symptoms.

AB - It has been hypothesized that the circadian pacemaker plays a role in major depressive disorder (MDD). We sought to determine if misalignment between the timing of sleep and the pacemaker correlated with symptom severity in MDD. Depression severity correlated with circadian misalignment: the more delayed, the more severe the symptoms.

KW - Circadian rhythms

KW - Depression

KW - Dim light melatonin onset (DLMO)

KW - Melatonin

KW - Phase angle difference (PAD)

KW - Sleep

UR - http://www.scopus.com/inward/record.url?scp=67650501503&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67650501503&partnerID=8YFLogxK

U2 - 10.1016/j.psychres.2009.04.009

DO - 10.1016/j.psychres.2009.04.009

M3 - Article

C2 - 19524304

AN - SCOPUS:67650501503

VL - 168

SP - 259

EP - 261

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

IS - 3

ER -