Circadian-Based Therapies for Circadian Rhythm Sleep-Wake Disorders

Helen J. Burgess, Jonathan Emens

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

This review summarizes recent developments relevant to the treatment of circadian rhythm sleep-wake disorders. The clinical practice guidelines for the treatment of intrinsic circadian rhythm sleep-wake disorders are described, followed by recent treatment studies for delayed sleep-wake phase disorder, non-24-hour sleep-wake disorder, irregular sleep-wake disorder, and shift work. New methods to estimate circadian phase, including home saliva collection to estimate the dim light melatonin onset, circadian questionnaires, and general rules to guide light and exogenous melatonin treatments, are described. New developments in light treatment are detailed, including light flashes during sleep and wearable light devices. Substances such as caffeine and alcohol, and devices such as electronic tablets are also considered for their potential to shift circadian timing. Finally, an update on melatonin supplements in the USA is discussed, along with the controversy surrounding the use of melatonin supplements in patients with prediabetes or diabetes.

Original languageEnglish (US)
Pages (from-to)158-165
Number of pages8
JournalCurrent Sleep Medicine Reports
Volume2
Issue number3
DOIs
StatePublished - Sep 1 2016

Fingerprint

Circadian Rhythm Sleep Disorders
Melatonin
Light
Intrinsic Sleep Disorders
Therapeutics
Prediabetic State
Equipment and Supplies
Caffeine
Saliva
Practice Guidelines
Tablets
Sleep
Alcohols
Sleep Wake Disorders

Keywords

  • Advance
  • Agonist
  • Alcohol
  • Caffeine
  • Delay
  • Diabetes
  • Light
  • Melatonin

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Neurology
  • Clinical Neurology

Cite this

Circadian-Based Therapies for Circadian Rhythm Sleep-Wake Disorders. / Burgess, Helen J.; Emens, Jonathan.

In: Current Sleep Medicine Reports, Vol. 2, No. 3, 01.09.2016, p. 158-165.

Research output: Contribution to journalReview article

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