Chronic treatment with vasopressin analogues alters affinity of vasopressin receptors in the septum and amygdala of the rat brain

Michael W. Swank, Daniel M. Dorsa

Research output: Contribution to journalArticle

12 Scopus citations


Accurel devices were used to administer AVP or AVP-antagonist into the lateral ventricle of the rat brain for 7 days. Neither AVP nor antagonist altered total binding site concentration in either septum or amygdala. However, treatment with antagonist caused a marked decrease in the affinity of the receptor for agonist in both the septum and amygdala.

Original languageEnglish (US)
Pages (from-to)342-344
Number of pages3
JournalBrain research
Issue number2
StatePublished - Mar 29 1991



  • Accurel colloidion device
  • Antagonist
  • Brain
  • Vasopressin receptor

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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