Chronic primary intestinal pseudo-obstruction

J. B. Hanks, W. C. Meyers, Dana Andersen, B. H. Woodard, W. P. Peete, J. T. Garbutt, R. S. Jones

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Chronic primary intestinal pseudo-obstruction (CPIP) has received increasing attention despite of its unclear etiology and infrequent occurrence. Recently a patient with this disorder had evidence of a primary visceral neuropathy. Reviewing the literature, we found 30 case reports of CPIP and evaluated their clinicopathologic findings. Presenting symptoms and radiologic findings were nonspecific. Esophageal motility was abnormal in 12 of 14 reports. Intestinal histopathology revealed normal muscle wall, mucosa, and ganglion cells in over 50% of reports. Only 48% of cases demonstrated clinical improvement. Thirty percent (8 of 30) ultimately died. We conclude that CPIP is a perplexing, often fatal entity that can mimic mechanical obstruction in the absence of definite etiology. Primary neurologic or muscular disease may be a possible explanation, but, as yet, definite documentation does not exist.

Original languageEnglish (US)
Pages (from-to)175-182
Number of pages8
JournalSurgery
Volume89
Issue number2
StatePublished - 1981
Externally publishedYes

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Intestinal Pseudo-Obstruction
Muscular Diseases
Nervous System Diseases
Ganglia
Documentation
Mucous Membrane
Muscles

ASJC Scopus subject areas

  • Surgery

Cite this

Hanks, J. B., Meyers, W. C., Andersen, D., Woodard, B. H., Peete, W. P., Garbutt, J. T., & Jones, R. S. (1981). Chronic primary intestinal pseudo-obstruction. Surgery, 89(2), 175-182.

Chronic primary intestinal pseudo-obstruction. / Hanks, J. B.; Meyers, W. C.; Andersen, Dana; Woodard, B. H.; Peete, W. P.; Garbutt, J. T.; Jones, R. S.

In: Surgery, Vol. 89, No. 2, 1981, p. 175-182.

Research output: Contribution to journalArticle

Hanks, JB, Meyers, WC, Andersen, D, Woodard, BH, Peete, WP, Garbutt, JT & Jones, RS 1981, 'Chronic primary intestinal pseudo-obstruction', Surgery, vol. 89, no. 2, pp. 175-182.
Hanks JB, Meyers WC, Andersen D, Woodard BH, Peete WP, Garbutt JT et al. Chronic primary intestinal pseudo-obstruction. Surgery. 1981;89(2):175-182.
Hanks, J. B. ; Meyers, W. C. ; Andersen, Dana ; Woodard, B. H. ; Peete, W. P. ; Garbutt, J. T. ; Jones, R. S. / Chronic primary intestinal pseudo-obstruction. In: Surgery. 1981 ; Vol. 89, No. 2. pp. 175-182.
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