Chronic obstructive pulmonary disease mortality and prevalence: The associations with smoking and poverty-A bold analysis

Peter Burney, Anamika Jithoo, Bernet Kato, Christer Janson, David Mannino, Ewa Nizankowska-Mogilnicka, Michael Studnicka, Wan Tan, Eric Bateman, Ali KoÇabas, William M. Vollmer, Thorarrin Gislason, Guy Marks, Parvaiz A. Koul, Imed Harrabi, Louisa Gnatiuc, Sonia Buist

Research output: Contribution to journalArticle

119 Scopus citations

Abstract

Background Chronic obstructive pulmonary disease (COPD) is a commonly reported cause of death and associated with smoking. However, COPD mortality is high in poor countries with low smoking rates. Spirometric restriction predicts mortality better than airflow obstruction, suggesting that the prevalence of restriction could explain mortality rates attributed to COPD. We have studied associations between mortality from COPD and low lung function, and between both lung function and death rates and cigarette consumption and gross national income per capita (GNI). Methods National COPD mortality rates were regressed against the prevalence of airflow obstruction and spirometric restriction in 22 Burden of Obstructive Lung Disease (BOLD) study sites and against GNI, and national smoking prevalence. The prevalence of airflow obstruction and spirometric restriction in the BOLD sites were regressed against GNI and mean pack years smoked.

Original languageEnglish (US)
Pages (from-to)465-473
Number of pages9
JournalThorax
Volume69
Issue number5
DOIs
StatePublished - May 2014

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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    Burney, P., Jithoo, A., Kato, B., Janson, C., Mannino, D., Nizankowska-Mogilnicka, E., Studnicka, M., Tan, W., Bateman, E., KoÇabas, A., Vollmer, W. M., Gislason, T., Marks, G., Koul, P. A., Harrabi, I., Gnatiuc, L., & Buist, S. (2014). Chronic obstructive pulmonary disease mortality and prevalence: The associations with smoking and poverty-A bold analysis. Thorax, 69(5), 465-473. https://doi.org/10.1136/thoraxjnl-2013-204460