Chronic obstructive pulmonary disease and bronchiectasis

Shannon A. Novosad, Alan F. Barker

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

PURPOSE OF REVIEW: Chronic obstructive pulmonary disease (COPD) and bronchiectasis are two different but related diseases that occur separately, but can coexist. In this review, we will examine the recent research regarding patients with COPD who have coexisting bronchiectasis. RECENT FINDINGS: Recent research has focused on defining distinct COPD phenotypes with the ultimate goal of changing the outcomes using tailored therapies. A frequent exacerbator phenotype has been identified. COPD patients with Pseudomonas aeruginosa are a phenotype with worse outcomes. Patients with coexisting COPD and bronchiectasis may represent a unique phenotype. SUMMARY: Patients with coexisting COPD and bronchiectasis could represent a unique phenotype with more severe disease, worse outcomes, more isolation of potentially pathogenic microorganisms, and more frequent exacerbations, with the potential for targeted therapies.

Original languageEnglish (US)
Pages (from-to)133-139
Number of pages7
JournalCurrent opinion in pulmonary medicine
Volume19
Issue number2
DOIs
StatePublished - Mar 2013

Keywords

  • COPD
  • bronchiectasis
  • phenotypes
  • prognosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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