Chronic maternal depression is associated with reduced weight gain in Latino infants from birth to 2 years of age

Janet M. Wojcicki, Katherine Holbrook, Robert H. Lustig, Elissa Epel, Aaron Caughey, Ricardo F. Muñoz, Stephen C. Shiboski, Melvin B. Heyman

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Background: Latino children are at increased risk for mirconutrient deficiencies and problems of overweight and obesity. Exposures in pregnancy and early postpartum may impact future growth trajectories. Objectives: To evaluate the relationship between prenatal and postnatal maternal depressive symptoms experienced in pregnancy and infant growth from birth to 2 years of age in a cohort of Latino infants. Methods: We recruited pregnant Latina mothers at two San Francisco hospitals and followed their healthy infants to 24 months of age. At 6, 12 and 24 months of age, infants were weighed and measured. Maternal depressive symptoms were assessed prenatally and at 4-6 weeks postpartum. Women who had high depressive symptoms at both time periods were defined as having chronic depression. Logistic mixed models were applied to compare growth curves and risk for overweight and underweight based on exposure to maternal depression. Results: We followed 181 infants to 24 months. At 12 and 24 months, respectively, 27.4% and 40.5% were overweight, and 5.6% and 2.2% were underweight. Exposure to chronic maternal depression was associated with underweight (OR = 12.12, 95%CI 1.86-78.78) and with reduced weight gain in the first 2 years of life (Coef = -0.48, 95% CI -0.94-0.01) compared with unexposed infants or infants exposed to episodic depression (depression at one time point). Exposure to chronic depression was also associated with reduced risk for overweight in the first 2 years of life (OR 0.28, 95%CI 0.03-0.92). Conclusions: Exposure to chronic maternal depression in the pre- and postnatal period was associated with reduced weight gain in the first two years of life and greater risk for failure to thrive, in comparison with unexposed infants or those exposed episodically. The infants of mothers with chronic depression may need additional nutritional monitoring and intervention.

Original languageEnglish (US)
Article numbere16737
JournalPLoS One
Volume6
Issue number2
DOIs
StatePublished - 2011
Externally publishedYes

Fingerprint

Hispanic Americans
Weight Gain
underweight
weight gain
Mothers
Parturition
Depression
signs and symptoms (animals and humans)
pregnancy
failure to thrive
infant growth
Thinness
postpartum period
infants
trajectories
Logistics
obesity
Trajectories
Postpartum Period
Monitoring

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Chronic maternal depression is associated with reduced weight gain in Latino infants from birth to 2 years of age. / Wojcicki, Janet M.; Holbrook, Katherine; Lustig, Robert H.; Epel, Elissa; Caughey, Aaron; Muñoz, Ricardo F.; Shiboski, Stephen C.; Heyman, Melvin B.

In: PLoS One, Vol. 6, No. 2, e16737, 2011.

Research output: Contribution to journalArticle

Wojcicki, JM, Holbrook, K, Lustig, RH, Epel, E, Caughey, A, Muñoz, RF, Shiboski, SC & Heyman, MB 2011, 'Chronic maternal depression is associated with reduced weight gain in Latino infants from birth to 2 years of age', PLoS One, vol. 6, no. 2, e16737. https://doi.org/10.1371/journal.pone.0016737
Wojcicki, Janet M. ; Holbrook, Katherine ; Lustig, Robert H. ; Epel, Elissa ; Caughey, Aaron ; Muñoz, Ricardo F. ; Shiboski, Stephen C. ; Heyman, Melvin B. / Chronic maternal depression is associated with reduced weight gain in Latino infants from birth to 2 years of age. In: PLoS One. 2011 ; Vol. 6, No. 2.
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abstract = "Background: Latino children are at increased risk for mirconutrient deficiencies and problems of overweight and obesity. Exposures in pregnancy and early postpartum may impact future growth trajectories. Objectives: To evaluate the relationship between prenatal and postnatal maternal depressive symptoms experienced in pregnancy and infant growth from birth to 2 years of age in a cohort of Latino infants. Methods: We recruited pregnant Latina mothers at two San Francisco hospitals and followed their healthy infants to 24 months of age. At 6, 12 and 24 months of age, infants were weighed and measured. Maternal depressive symptoms were assessed prenatally and at 4-6 weeks postpartum. Women who had high depressive symptoms at both time periods were defined as having chronic depression. Logistic mixed models were applied to compare growth curves and risk for overweight and underweight based on exposure to maternal depression. Results: We followed 181 infants to 24 months. At 12 and 24 months, respectively, 27.4{\%} and 40.5{\%} were overweight, and 5.6{\%} and 2.2{\%} were underweight. Exposure to chronic maternal depression was associated with underweight (OR = 12.12, 95{\%}CI 1.86-78.78) and with reduced weight gain in the first 2 years of life (Coef = -0.48, 95{\%} CI -0.94-0.01) compared with unexposed infants or infants exposed to episodic depression (depression at one time point). Exposure to chronic depression was also associated with reduced risk for overweight in the first 2 years of life (OR 0.28, 95{\%}CI 0.03-0.92). Conclusions: Exposure to chronic maternal depression in the pre- and postnatal period was associated with reduced weight gain in the first two years of life and greater risk for failure to thrive, in comparison with unexposed infants or those exposed episodically. The infants of mothers with chronic depression may need additional nutritional monitoring and intervention.",
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T1 - Chronic maternal depression is associated with reduced weight gain in Latino infants from birth to 2 years of age

AU - Wojcicki, Janet M.

AU - Holbrook, Katherine

AU - Lustig, Robert H.

AU - Epel, Elissa

AU - Caughey, Aaron

AU - Muñoz, Ricardo F.

AU - Shiboski, Stephen C.

AU - Heyman, Melvin B.

PY - 2011

Y1 - 2011

N2 - Background: Latino children are at increased risk for mirconutrient deficiencies and problems of overweight and obesity. Exposures in pregnancy and early postpartum may impact future growth trajectories. Objectives: To evaluate the relationship between prenatal and postnatal maternal depressive symptoms experienced in pregnancy and infant growth from birth to 2 years of age in a cohort of Latino infants. Methods: We recruited pregnant Latina mothers at two San Francisco hospitals and followed their healthy infants to 24 months of age. At 6, 12 and 24 months of age, infants were weighed and measured. Maternal depressive symptoms were assessed prenatally and at 4-6 weeks postpartum. Women who had high depressive symptoms at both time periods were defined as having chronic depression. Logistic mixed models were applied to compare growth curves and risk for overweight and underweight based on exposure to maternal depression. Results: We followed 181 infants to 24 months. At 12 and 24 months, respectively, 27.4% and 40.5% were overweight, and 5.6% and 2.2% were underweight. Exposure to chronic maternal depression was associated with underweight (OR = 12.12, 95%CI 1.86-78.78) and with reduced weight gain in the first 2 years of life (Coef = -0.48, 95% CI -0.94-0.01) compared with unexposed infants or infants exposed to episodic depression (depression at one time point). Exposure to chronic depression was also associated with reduced risk for overweight in the first 2 years of life (OR 0.28, 95%CI 0.03-0.92). Conclusions: Exposure to chronic maternal depression in the pre- and postnatal period was associated with reduced weight gain in the first two years of life and greater risk for failure to thrive, in comparison with unexposed infants or those exposed episodically. The infants of mothers with chronic depression may need additional nutritional monitoring and intervention.

AB - Background: Latino children are at increased risk for mirconutrient deficiencies and problems of overweight and obesity. Exposures in pregnancy and early postpartum may impact future growth trajectories. Objectives: To evaluate the relationship between prenatal and postnatal maternal depressive symptoms experienced in pregnancy and infant growth from birth to 2 years of age in a cohort of Latino infants. Methods: We recruited pregnant Latina mothers at two San Francisco hospitals and followed their healthy infants to 24 months of age. At 6, 12 and 24 months of age, infants were weighed and measured. Maternal depressive symptoms were assessed prenatally and at 4-6 weeks postpartum. Women who had high depressive symptoms at both time periods were defined as having chronic depression. Logistic mixed models were applied to compare growth curves and risk for overweight and underweight based on exposure to maternal depression. Results: We followed 181 infants to 24 months. At 12 and 24 months, respectively, 27.4% and 40.5% were overweight, and 5.6% and 2.2% were underweight. Exposure to chronic maternal depression was associated with underweight (OR = 12.12, 95%CI 1.86-78.78) and with reduced weight gain in the first 2 years of life (Coef = -0.48, 95% CI -0.94-0.01) compared with unexposed infants or infants exposed to episodic depression (depression at one time point). Exposure to chronic depression was also associated with reduced risk for overweight in the first 2 years of life (OR 0.28, 95%CI 0.03-0.92). Conclusions: Exposure to chronic maternal depression in the pre- and postnatal period was associated with reduced weight gain in the first two years of life and greater risk for failure to thrive, in comparison with unexposed infants or those exposed episodically. The infants of mothers with chronic depression may need additional nutritional monitoring and intervention.

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