Chronic kidney diseases in agricultural communities: report from a workshop

Susan R. Mendley, Adeera Levin, Ricardo Correa-Rotter, Bonnie R. Joubert, Elizabeth A. Whelan, Brian Curwin, Erik H. Koritzinsky, Denise M. Gaughan, Paul L. Kimmel, Shuchi Anand, Pedro Ordunez, Ludovic Reveiz, Diane S. Rohlman, Madeleine K. Scammell, Robert O. Wright, Robert A. Star

Research output: Contribution to journalArticle

Abstract

In June 2018, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute of Environmental Health Sciences sponsored a workshop to identify research gaps in an increasingly common form of chronic kidney disease in agricultural communities, often termed “CKDu.” The organizers invited a broad range of experts who provided diverse expertise and perspectives, many of whom had never addressed this particular epidemic. Discussion was focused around selected topics, including identifying and mitigating barriers to research in CKDu, creating a case definition, and defining common data elements. All hypotheses regarding etiology were entertained, and meeting participants discussed potential research strategies, choices in study design, and novel tools that may prove useful in this disease. Achievements of the workshop included robust cross-disciplinary discussion and preliminary planning of research goals and design. Specific challenges in implementing basic and clinical research and interventions in low- and middle-income countries were recognized. A balanced approach to leveraging local resources and capacity building without overreaching was emphasized.

Original languageEnglish (US)
Pages (from-to)1071-1076
Number of pages6
JournalKidney International
Volume96
Issue number5
DOIs
Publication statusPublished - Nov 2019

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Keywords

  • chronic interstitial nephritis of agricultural communities
  • chronic kidney disease of uncertain/nontraditional etiology
  • environmental exposure
  • kidney disease of unknown cause in agricultural laborers
  • low- and middle-income countries
  • Mesoamerican nephropathy
  • tubulointerstitial

ASJC Scopus subject areas

  • Nephrology

Cite this

Mendley, S. R., Levin, A., Correa-Rotter, R., Joubert, B. R., Whelan, E. A., Curwin, B., ... Star, R. A. (2019). Chronic kidney diseases in agricultural communities: report from a workshop. Kidney International, 96(5), 1071-1076. https://doi.org/10.1016/j.kint.2019.06.024