Chronic cough and hoarseness in patients with severe gastroesophageal reflux disease - Diagnosis and response to therapy

J. Patrick Waring, Leonel Lacayo, John Hunter, Ellen Katz, Barbara Suwak

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

Gastroesophageal reflux may be responsible for atypical symptoms such as chronic cough and hoarseness. Our aim was to evaluate and treat patients with severe gastroesophageal reflux and chronic cough or hoarseness with intensive antireflux therapy. Twenty-seven patients with typical heartburn symptoms in addition to significant cough or hoarseness were treated with aggressive antireflux therapy. We recorded the response of each symptom to the antireflux therapy. Two patients were lost to follow-up. Twenty of the 25 (80%) patients showed some improvement in cough or hoarseness, nine (36%) had no atypical symptoms at follow-up. The response of heartburn to therapy was strongly predictive of successful therapy for the atypical symptoms. Cough and hoarseness improved in only two of the five patients with residual heartburn symptoms compared to 18 of 20 patients with no heartburn (P

Original languageEnglish (US)
Pages (from-to)1093-1097
Number of pages5
JournalDigestive Diseases and Sciences
Volume40
Issue number5
DOIs
StatePublished - May 1995
Externally publishedYes

Fingerprint

Hoarseness
Gastroesophageal Reflux
Cough
Heartburn
Therapeutics
Lost to Follow-Up

Keywords

  • antireflux therapy
  • chronic cough
  • gastroesophageal reflux
  • hoarseness

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Chronic cough and hoarseness in patients with severe gastroesophageal reflux disease - Diagnosis and response to therapy. / Patrick Waring, J.; Lacayo, Leonel; Hunter, John; Katz, Ellen; Suwak, Barbara.

In: Digestive Diseases and Sciences, Vol. 40, No. 5, 05.1995, p. 1093-1097.

Research output: Contribution to journalArticle

Patrick Waring, J. ; Lacayo, Leonel ; Hunter, John ; Katz, Ellen ; Suwak, Barbara. / Chronic cough and hoarseness in patients with severe gastroesophageal reflux disease - Diagnosis and response to therapy. In: Digestive Diseases and Sciences. 1995 ; Vol. 40, No. 5. pp. 1093-1097.
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