Chromosome aberrations in solid tumors

Donna G. Albertson, Colin Collins, Frank McCormick, Joe Gray

Research output: Contribution to journalArticle

561 Citations (Scopus)

Abstract

Chromosome aberrations in human solid tumors are hallmarks of gene deregulation and genome instability. This review summarizes current knowledge regarding aberrations, discusses their functional importance, suggests mechanisms by which aberrations may form during cancer progression and provides examples of clinical advances that have come from studies of chromosome aberrations.

Original languageEnglish (US)
Pages (from-to)369-376
Number of pages8
JournalNature Genetics
Volume34
Issue number4
DOIs
StatePublished - Aug 1 2003
Externally publishedYes

Fingerprint

Chromosome Aberrations
Genomic Instability
Neoplasms
Genes

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

Cite this

Albertson, D. G., Collins, C., McCormick, F., & Gray, J. (2003). Chromosome aberrations in solid tumors. Nature Genetics, 34(4), 369-376. https://doi.org/10.1038/ng1215

Chromosome aberrations in solid tumors. / Albertson, Donna G.; Collins, Colin; McCormick, Frank; Gray, Joe.

In: Nature Genetics, Vol. 34, No. 4, 01.08.2003, p. 369-376.

Research output: Contribution to journalArticle

Albertson, DG, Collins, C, McCormick, F & Gray, J 2003, 'Chromosome aberrations in solid tumors', Nature Genetics, vol. 34, no. 4, pp. 369-376. https://doi.org/10.1038/ng1215
Albertson DG, Collins C, McCormick F, Gray J. Chromosome aberrations in solid tumors. Nature Genetics. 2003 Aug 1;34(4):369-376. https://doi.org/10.1038/ng1215
Albertson, Donna G. ; Collins, Colin ; McCormick, Frank ; Gray, Joe. / Chromosome aberrations in solid tumors. In: Nature Genetics. 2003 ; Vol. 34, No. 4. pp. 369-376.
@article{0bd0061dcbe148a9abcb2e34686c69ce,
title = "Chromosome aberrations in solid tumors",
abstract = "Chromosome aberrations in human solid tumors are hallmarks of gene deregulation and genome instability. This review summarizes current knowledge regarding aberrations, discusses their functional importance, suggests mechanisms by which aberrations may form during cancer progression and provides examples of clinical advances that have come from studies of chromosome aberrations.",
author = "Albertson, {Donna G.} and Colin Collins and Frank McCormick and Joe Gray",
year = "2003",
month = "8",
day = "1",
doi = "10.1038/ng1215",
language = "English (US)",
volume = "34",
pages = "369--376",
journal = "Nature Genetics",
issn = "1061-4036",
publisher = "Nature Publishing Group",
number = "4",

}

TY - JOUR

T1 - Chromosome aberrations in solid tumors

AU - Albertson, Donna G.

AU - Collins, Colin

AU - McCormick, Frank

AU - Gray, Joe

PY - 2003/8/1

Y1 - 2003/8/1

N2 - Chromosome aberrations in human solid tumors are hallmarks of gene deregulation and genome instability. This review summarizes current knowledge regarding aberrations, discusses their functional importance, suggests mechanisms by which aberrations may form during cancer progression and provides examples of clinical advances that have come from studies of chromosome aberrations.

AB - Chromosome aberrations in human solid tumors are hallmarks of gene deregulation and genome instability. This review summarizes current knowledge regarding aberrations, discusses their functional importance, suggests mechanisms by which aberrations may form during cancer progression and provides examples of clinical advances that have come from studies of chromosome aberrations.

UR - http://www.scopus.com/inward/record.url?scp=0042166174&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0042166174&partnerID=8YFLogxK

U2 - 10.1038/ng1215

DO - 10.1038/ng1215

M3 - Article

C2 - 12923544

AN - SCOPUS:0042166174

VL - 34

SP - 369

EP - 376

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 4

ER -