Chromosomal localization of the γ-glutamyl carboxylase gene at 2p12

Wen Lin Kuo, Darrel W. Stafford, Jesús Cruces, Joe Gray, Solera Jesú

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

We have used two complementary approaches to analyze the chromosomal location of the γ-glutamyl carboxylase gene. The amplification of a carboxylase-specific genomic fragment by polymerase chain reaction (PCR) in a human-rodent hybrid cell mapping panel localized the gene to chromosome 2. Mapping by fluorescence in situ hybridization assigned the gene to p12 of chromosome 2. Our results indicate that the γ-glutamyl carboxylase gene has a single locus in the human genome.

Original languageEnglish (US)
Pages (from-to)746-748
Number of pages3
JournalGenomics
Volume25
Issue number3
DOIs
StatePublished - Feb 10 1995
Externally publishedYes

Fingerprint

Chromosomes, Human, Pair 2
Genes
Hybrid Cells
Human Genome
Fluorescence In Situ Hybridization
Rodentia
Polymerase Chain Reaction
glutamyl carboxylase

ASJC Scopus subject areas

  • Genetics

Cite this

Chromosomal localization of the γ-glutamyl carboxylase gene at 2p12. / Kuo, Wen Lin; Stafford, Darrel W.; Cruces, Jesús; Gray, Joe; Jesú, Solera.

In: Genomics, Vol. 25, No. 3, 10.02.1995, p. 746-748.

Research output: Contribution to journalArticle

Kuo, Wen Lin ; Stafford, Darrel W. ; Cruces, Jesús ; Gray, Joe ; Jesú, Solera. / Chromosomal localization of the γ-glutamyl carboxylase gene at 2p12. In: Genomics. 1995 ; Vol. 25, No. 3. pp. 746-748.
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