Chorioretinal architecture in Aicardi syndrome: An optical coherence tomography and fluorescein angiography study

Joseph N. Martel; Tina Rutar; Brandon J. Lujan; Alejandra De Alba Campomanes

doi:10.1016/j.jaapos.2011.03.011

Chorioretinal architecture in Aicardi syndrome: An optical coherence tomography and fluorescein angiography study

Joseph N. Martel, Tina Rutar, Brandon J. Lujan, Alejandra De Alba Campomanes

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Aicardi syndrome is a rare congenital disorder with a classic triad of infantile spasms, chorioretinal lacunae, and agenesis of the corpus callosum. We report the use of fluorescein angiography and spectral domain optical coherence tomography to examine the posterior segment structures in an 8-month-old girl with Aicardi syndrome. Most of the observed features correlated with previously published histopathological findings, but inner nuclear layer cysts have not been previously described. To our knowledge, this is the first study of the tomographic and angiographic chorioretinal features in vivo.

Original language	English (US)
Pages (from-to)	308-310
Number of pages	3
Journal	Journal of AAPOS
Volume	15
Issue number	3
DOIs	https://doi.org/10.1016/j.jaapos.2011.03.011
State	Published - Jun 2011
Externally published	Yes

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Ophthalmology

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10.1016/j.jaapos.2011.03.011

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@article{310b527332094f23a9e53aa1185a8ab1,

title = "Chorioretinal architecture in Aicardi syndrome: An optical coherence tomography and fluorescein angiography study",

abstract = "Aicardi syndrome is a rare congenital disorder with a classic triad of infantile spasms, chorioretinal lacunae, and agenesis of the corpus callosum. We report the use of fluorescein angiography and spectral domain optical coherence tomography to examine the posterior segment structures in an 8-month-old girl with Aicardi syndrome. Most of the observed features correlated with previously published histopathological findings, but inner nuclear layer cysts have not been previously described. To our knowledge, this is the first study of the tomographic and angiographic chorioretinal features in vivo.",

author = "Martel, {Joseph N.} and Tina Rutar and Lujan, {Brandon J.} and {De Alba Campomanes}, Alejandra",

note = "Funding Information: Brandon J Lujan, MD, is supported by a National Institutes of Health K12 Award . This study was supported by a grant to the UCSF Visual Center for the Child from the Wayne and Gladys Valley Foundation, Oakland, California, and by a UCSF institutional P30 core grant from the National Institutes of Health , NEI EY002162-31 . The sponsor or funding organization had no role in the design or conduct of the study, data analysis, or manuscript preparation. Alejandra de Alba Campomanes, MD, had full access to all the data in the study and takes responsibility for the integrity of the data and its accuracy. ",

year = "2011",

month = jun,

doi = "10.1016/j.jaapos.2011.03.011",

language = "English (US)",

volume = "15",

pages = "308--310",

journal = "Journal of AAPOS",

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AU - Martel, Joseph N.

AU - Rutar, Tina

AU - Lujan, Brandon J.

AU - De Alba Campomanes, Alejandra

N1 - Funding Information: Brandon J Lujan, MD, is supported by a National Institutes of Health K12 Award . This study was supported by a grant to the UCSF Visual Center for the Child from the Wayne and Gladys Valley Foundation, Oakland, California, and by a UCSF institutional P30 core grant from the National Institutes of Health , NEI EY002162-31 . The sponsor or funding organization had no role in the design or conduct of the study, data analysis, or manuscript preparation. Alejandra de Alba Campomanes, MD, had full access to all the data in the study and takes responsibility for the integrity of the data and its accuracy.

PY - 2011/6

Y1 - 2011/6

N2 - Aicardi syndrome is a rare congenital disorder with a classic triad of infantile spasms, chorioretinal lacunae, and agenesis of the corpus callosum. We report the use of fluorescein angiography and spectral domain optical coherence tomography to examine the posterior segment structures in an 8-month-old girl with Aicardi syndrome. Most of the observed features correlated with previously published histopathological findings, but inner nuclear layer cysts have not been previously described. To our knowledge, this is the first study of the tomographic and angiographic chorioretinal features in vivo.

AB - Aicardi syndrome is a rare congenital disorder with a classic triad of infantile spasms, chorioretinal lacunae, and agenesis of the corpus callosum. We report the use of fluorescein angiography and spectral domain optical coherence tomography to examine the posterior segment structures in an 8-month-old girl with Aicardi syndrome. Most of the observed features correlated with previously published histopathological findings, but inner nuclear layer cysts have not been previously described. To our knowledge, this is the first study of the tomographic and angiographic chorioretinal features in vivo.

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Chorioretinal architecture in Aicardi syndrome: An optical coherence tomography and fluorescein angiography study

Abstract

ASJC Scopus subject areas

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