Cholinergic Signaling through Synaptic SK Channels: It's a Protein Kinase but Which One?

James Maylie, John P. Adelman

Research output: Contribution to journalShort survey

9 Scopus citations


Cholinergic signaling modulates synaptic responses and influences cognition. In this issue of Neuron, two groups (Buchanan et al. and Giessel and Sabatini) present evidence that cholinergic signaling enhances postsynaptic responses in CA1 neurons by decreasing synaptic SK channel activity. However, they come to different conclusions about the protein kinases involved in this process.

Original languageEnglish (US)
Pages (from-to)809-811
Number of pages3
Issue number5
StatePublished - Dec 9 2010


ASJC Scopus subject areas

  • Neuroscience(all)

Cite this