Cholinergic Signaling through Synaptic SK Channels: It's a Protein Kinase but Which One?

James Maylie; John P. Adelman

doi:10.1016/j.neuron.2010.11.037

Cholinergic Signaling through Synaptic SK Channels: It's a Protein Kinase but Which One?

James Maylie, John P. Adelman

Obstetrics and Gynecology

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

Cholinergic signaling modulates synaptic responses and influences cognition. In this issue of Neuron, two groups (Buchanan et al. and Giessel and Sabatini) present evidence that cholinergic signaling enhances postsynaptic responses in CA1 neurons by decreasing synaptic SK channel activity. However, they come to different conclusions about the protein kinases involved in this process.

Original language	English (US)
Pages (from-to)	809-811
Number of pages	3
Journal	Neuron
Volume	68
Issue number	5
DOIs	https://doi.org/10.1016/j.neuron.2010.11.037
State	Published - Dec 9 2010

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.neuron.2010.11.037

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title = "Cholinergic Signaling through Synaptic SK Channels: It's a Protein Kinase but Which One?",

abstract = "Cholinergic signaling modulates synaptic responses and influences cognition. In this issue of Neuron, two groups (Buchanan et al. and Giessel and Sabatini) present evidence that cholinergic signaling enhances postsynaptic responses in CA1 neurons by decreasing synaptic SK channel activity. However, they come to different conclusions about the protein kinases involved in this process.",

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AU - Maylie, James

AU - Adelman, John P.

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N2 - Cholinergic signaling modulates synaptic responses and influences cognition. In this issue of Neuron, two groups (Buchanan et al. and Giessel and Sabatini) present evidence that cholinergic signaling enhances postsynaptic responses in CA1 neurons by decreasing synaptic SK channel activity. However, they come to different conclusions about the protein kinases involved in this process.

AB - Cholinergic signaling modulates synaptic responses and influences cognition. In this issue of Neuron, two groups (Buchanan et al. and Giessel and Sabatini) present evidence that cholinergic signaling enhances postsynaptic responses in CA1 neurons by decreasing synaptic SK channel activity. However, they come to different conclusions about the protein kinases involved in this process.

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Cholinergic Signaling through Synaptic SK Channels: It's a Protein Kinase but Which One?

Abstract

ASJC Scopus subject areas

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