Chlorella virus PBCV-1 encodes a homolog of the bacteriophage T4 UV damage repair gene denV

Masakazu Furuta, John O. Schrader, Holly S. Schrader, Tyler A. Kokjohn, Simon Nyaga, Amanda McCullough, Robert (Stephen) Lloyd, Dwight E. Burbank, Dorit Landstein, Les Lane, James L. Van Etten

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

The bacteriophage T4 denV gene encodes a well-characterized DNA repair enzyme involved in pyrimidine photodimer excision. We have discovered the first homologs of the denV gene in chlorella viruses, which are common in fresh water. This gene functions in vivo and also when cloned in Escherichia coli. Photodamaged virus DNA can also be photoreactivated by the host chlorella. Since the chlorella viruses are continually exposed to solar radiation in their native environments, two separate DNA repair systems, one that functions in the dark and one that functions in the light, significantly enhance their survival.

Original languageEnglish (US)
Pages (from-to)1551-1556
Number of pages6
JournalApplied and Environmental Microbiology
Volume63
Issue number4
StatePublished - Apr 1997
Externally publishedYes

Fingerprint

Paramecium bursaria Chlorella virus 1
Chlorella
Bacteriophage T4
bacteriophage
bacteriophages
repair
virus
DNA repair
Viruses
DNA
viruses
damage
gene
DNA Repair Enzymes
Genes
DNA viruses
DNA Viruses
genes
pyrimidines
Fresh Water

ASJC Scopus subject areas

  • Environmental Science(all)
  • Biotechnology
  • Microbiology

Cite this

Furuta, M., Schrader, J. O., Schrader, H. S., Kokjohn, T. A., Nyaga, S., McCullough, A., ... Van Etten, J. L. (1997). Chlorella virus PBCV-1 encodes a homolog of the bacteriophage T4 UV damage repair gene denV. Applied and Environmental Microbiology, 63(4), 1551-1556.

Chlorella virus PBCV-1 encodes a homolog of the bacteriophage T4 UV damage repair gene denV. / Furuta, Masakazu; Schrader, John O.; Schrader, Holly S.; Kokjohn, Tyler A.; Nyaga, Simon; McCullough, Amanda; Lloyd, Robert (Stephen); Burbank, Dwight E.; Landstein, Dorit; Lane, Les; Van Etten, James L.

In: Applied and Environmental Microbiology, Vol. 63, No. 4, 04.1997, p. 1551-1556.

Research output: Contribution to journalArticle

Furuta, M, Schrader, JO, Schrader, HS, Kokjohn, TA, Nyaga, S, McCullough, A, Lloyd, RS, Burbank, DE, Landstein, D, Lane, L & Van Etten, JL 1997, 'Chlorella virus PBCV-1 encodes a homolog of the bacteriophage T4 UV damage repair gene denV', Applied and Environmental Microbiology, vol. 63, no. 4, pp. 1551-1556.
Furuta, Masakazu ; Schrader, John O. ; Schrader, Holly S. ; Kokjohn, Tyler A. ; Nyaga, Simon ; McCullough, Amanda ; Lloyd, Robert (Stephen) ; Burbank, Dwight E. ; Landstein, Dorit ; Lane, Les ; Van Etten, James L. / Chlorella virus PBCV-1 encodes a homolog of the bacteriophage T4 UV damage repair gene denV. In: Applied and Environmental Microbiology. 1997 ; Vol. 63, No. 4. pp. 1551-1556.
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