Characterization of Moraxella (Branhamella) catarrhalis lbpB, lbpA, and lactoferrin receptor orf3 isogenic mutants

Robert A. Bonnah, Henry Wong, Sheena M. Loosmore, Anthony B. Schryvers

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

Pathogenic members of the family Neisseriaceae produce specific receptors to acquire iron from their host's lactoferrin and transferrin. Recently, putative Moraxella catarrhalis lactoferrin receptor genes and a third open reading frame (lbpB, IbpA, and orf3) were cloned and sequenced. We describe the preliminary characterization of isogenic mutants deficient in LbpB, LbpA, or Orf3 protein.

Original languageEnglish (US)
Pages (from-to)1517-1520
Number of pages4
JournalInfection and Immunity
Volume67
Issue number3
DOIs
StatePublished - Mar 1999

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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