Characterization of human FSD1, a novel brain specific gene on chromosome 19 with paralogy to 9q31

Laura Carim-Todd; Mònica Escarceller; Xavier Estivill; Lauro Sumoy

doi:10.1016/S0167-4781(01)00178-6

Characterization of human FSD1, a novel brain specific gene on chromosome 19 with paralogy to 9q31

Laura Carim-Todd, Mònica Escarceller, Xavier Estivill, Lauro Sumoy

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

We have characterized a novel human gene, FSD1, on chromosome 19. FSD1 has a BBC, FN3 and SPRY domain, it is distantly related to the midline 1 gene and is expressed only in the brain. We have established its exon-intron structure and we have identified the corresponding orthologous genes in other species. In addition, the identification of FSD1 has led us to identify a homologous counterpart sequence on chromosome 9.

Original language	English (US)
Pages (from-to)	200-203
Number of pages	4
Journal	Biochimica et Biophysica Acta - Gene Structure and Expression
Volume	1518
Issue number	1-2
DOIs	https://doi.org/10.1016/S0167-4781(01)00178-6
State	Published - Mar 19 2001
Externally published	Yes

Keywords

BBC domain
EUROIMAGE
FN3 domain
FSD1 domain
FSD1L
Paralogy
SPRY domain
cDNA sequencing

ASJC Scopus subject areas

Structural Biology
Biophysics
Biochemistry
Genetics

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10.1016/S0167-4781(01)00178-6

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title = "Characterization of human FSD1, a novel brain specific gene on chromosome 19 with paralogy to 9q31",

abstract = "We have characterized a novel human gene, FSD1, on chromosome 19. FSD1 has a BBC, FN3 and SPRY domain, it is distantly related to the midline 1 gene and is expressed only in the brain. We have established its exon-intron structure and we have identified the corresponding orthologous genes in other species. In addition, the identification of FSD1 has led us to identify a homologous counterpart sequence on chromosome 9.",

keywords = "BBC domain, EUROIMAGE, FN3 domain, FSD1 domain, FSD1L, Paralogy, SPRY domain, cDNA sequencing",

author = "Laura Carim-Todd and M{\`o}nica Escarceller and Xavier Estivill and Lauro Sumoy",

note = "Funding Information: We are grateful to A. Puig and D. Otero, the HGMP Resource Center in Hinxton, UK, and the RZPD in Berlin, Germany. Supported by EU Biomed Project No. BMH4-CT97-2284 to X.E. and by CICYT-IN95-0347. M.E. is funded by the Spanish Ministry of Education (CIDYT contract FPI-070-97) and L.S. by the Catalan autonomous government (CIRIT-RED contract 1998-64).",

year = "2001",

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doi = "10.1016/S0167-4781(01)00178-6",

language = "English (US)",

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pages = "200--203",

journal = "Biochimica et Biophysica Acta - Gene Structure and Expression",

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T1 - Characterization of human FSD1, a novel brain specific gene on chromosome 19 with paralogy to 9q31

AU - Carim-Todd, Laura

AU - Escarceller, Mònica

AU - Estivill, Xavier

AU - Sumoy, Lauro

N1 - Funding Information: We are grateful to A. Puig and D. Otero, the HGMP Resource Center in Hinxton, UK, and the RZPD in Berlin, Germany. Supported by EU Biomed Project No. BMH4-CT97-2284 to X.E. and by CICYT-IN95-0347. M.E. is funded by the Spanish Ministry of Education (CIDYT contract FPI-070-97) and L.S. by the Catalan autonomous government (CIRIT-RED contract 1998-64).

PY - 2001/3/19

Y1 - 2001/3/19

N2 - We have characterized a novel human gene, FSD1, on chromosome 19. FSD1 has a BBC, FN3 and SPRY domain, it is distantly related to the midline 1 gene and is expressed only in the brain. We have established its exon-intron structure and we have identified the corresponding orthologous genes in other species. In addition, the identification of FSD1 has led us to identify a homologous counterpart sequence on chromosome 9.

AB - We have characterized a novel human gene, FSD1, on chromosome 19. FSD1 has a BBC, FN3 and SPRY domain, it is distantly related to the midline 1 gene and is expressed only in the brain. We have established its exon-intron structure and we have identified the corresponding orthologous genes in other species. In addition, the identification of FSD1 has led us to identify a homologous counterpart sequence on chromosome 9.

KW - BBC domain

KW - EUROIMAGE

KW - FN3 domain

KW - FSD1 domain

KW - FSD1L

KW - Paralogy

KW - SPRY domain

KW - cDNA sequencing

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DO - 10.1016/S0167-4781(01)00178-6

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AN - SCOPUS:0035911733

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JO - Biochimica et Biophysica Acta - Gene Structure and Expression

JF - Biochimica et Biophysica Acta - Gene Structure and Expression

IS - 1-2

ER -

Characterization of human FSD1, a novel brain specific gene on chromosome 19 with paralogy to 9q31

Abstract

Keywords

ASJC Scopus subject areas

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