Characterization of an immunogenic glycocalyx on the surfaces of Cryptosporidium parvum oocysts and sporozoites

Jayasri Nanduri, Selvi Williams, Aji Toshiki, Timothy P. Flanigan

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Ruthenium red staining of Cryptosporidium parvum oocysts revealed the presence of a carbohydrate matrix on their outer bilayers that is characteristic of a glycocalyx. Surface labeling of intact oocysts identified material of high molecular weight (> 106) that reacted positively with sera from cryptosporidium-infected patients and with immunoglobulin A monoclonal antibodies.

Original languageEnglish (US)
Pages (from-to)2022-2024
Number of pages3
JournalInfection and Immunity
Volume67
Issue number4
DOIs
StatePublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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