Characterization of a pulsatile rotary total artificial heart

Patrick L. Jurney, Jeremy J. Glynn, Igor V. Dykan, Matthew W. Hagen, Sanjiv Kaul, Richard K. Wampler, Monica T. Hinds, George D. Giraud

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


This article describes the properties and performance of a rotary total artificial heart (TAH) that produces inherently pulsatile flow. The hydraulic performance of the TAH was characterized using a mock circulatory loop to simulate four physiologically relevant conditions: baseline flow, increased flow, systemic hypertension, and pulmonary hypertension. The pump has a variable shuttle rate (beats per minute), percentage dwell time, and angular velocity on either side (revolutions per minute), which allows for full control of the flow rate and pulsatility over a range of healthy and pathologic pressures and flow rates. The end-to-end length and displacement volume of the TAH are 9.8 cm and 130 mL, respectively, allowing it to fit in smaller chest cavities including those of smaller adults and juvenile humans.

Original languageEnglish (US)
Pages (from-to)135-142
Number of pages8
JournalArtificial Organs
Issue number2
StatePublished - Feb 2021


  • cardiovascular devices
  • heart failure
  • total artificial heart

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering


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