Characterization of a pulsatile rotary total artificial heart

Patrick L. Jurney, Jeremy J. Glynn, Igor V. Dykan, Matthew W. Hagen, Sanjiv Kaul, Richard Wampler, Monica T. Hinds, George D. Giraud

Research output: Contribution to journalArticlepeer-review

Abstract

This article describes the properties and performance of a rotary total artificial heart (TAH) that produces inherently pulsatile flow. The hydraulic performance of the TAH was characterized using a mock circulatory loop to simulate four physiologically relevant conditions: baseline flow, increased flow, systemic hypertension, and pulmonary hypertension. The pump has a variable shuttle rate (beats per minute), percentage dwell time, and angular velocity on either side (revolutions per minute), which allows for full control of the flow rate and pulsatility over a range of healthy and pathologic pressures and flow rates. The end-to-end length and displacement volume of the TAH are 9.8 cm and 130 mL, respectively, allowing it to fit in smaller chest cavities including those of smaller adults and juvenile humans.

Original languageEnglish (US)
JournalArtificial Organs
DOIs
StateAccepted/In press - 2020

Keywords

  • cardiovascular devices
  • heart failure
  • total artificial heart

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering

Fingerprint Dive into the research topics of 'Characterization of a pulsatile rotary total artificial heart'. Together they form a unique fingerprint.

Cite this