Channel-forming toxins: Tales of transformation

Research output: Contribution to journalArticle

132 Citations (Scopus)

Abstract

Channel-forming bacterial toxins undergo a series of remarkable changes in solubility, oligomerization state, structure and dynamics during the processes of membrane binding, assembly, membrane insertion and channel formation. Recent high-resolution crystal structures of channel-forming toxins, in both water-soluble and membrane-bound, channel-formed states, have brought a wealth of new information to bear on issues of structure, mechanism and function.

Original languageEnglish (US)
Pages (from-to)566-573
Number of pages8
JournalCurrent Opinion in Structural Biology
Volume7
Issue number4
DOIs
StatePublished - Aug 1997
Externally publishedYes

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Ion Channels
Bacterial Toxins
Solubility
Membranes
Water

ASJC Scopus subject areas

  • Molecular Biology
  • Structural Biology

Cite this

Channel-forming toxins : Tales of transformation. / Gouaux, Eric.

In: Current Opinion in Structural Biology, Vol. 7, No. 4, 08.1997, p. 566-573.

Research output: Contribution to journalArticle

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