Channel-forming toxins: Tales of transformation

Eric Gouaux

Research output: Contribution to journalArticlepeer-review

151 Scopus citations


Channel-forming bacterial toxins undergo a series of remarkable changes in solubility, oligomerization state, structure and dynamics during the processes of membrane binding, assembly, membrane insertion and channel formation. Recent high-resolution crystal structures of channel-forming toxins, in both water-soluble and membrane-bound, channel-formed states, have brought a wealth of new information to bear on issues of structure, mechanism and function.

Original languageEnglish (US)
Pages (from-to)566-573
Number of pages8
JournalCurrent Opinion in Structural Biology
Issue number4
StatePublished - Aug 1997
Externally publishedYes

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology


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